Disruption of MyD88 signaling suppresses hemophagocytic lymphohistiocytosis in mice

Hemophagocytic lymphohistiocytosis (HLH) is a rare inflammatory disorder with a poor prognosis for affected individuals. To find a means of suppressing the clinical phenotype, we investigated the cellular and molecular mechanisms leading to HLH in Unc13d(jinx/jinx) mice, in which cytolytic function...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Krebs, Philippe, Crozat, Karine, Popkin, Daniel, Oldstone, Michael B., Beutler, Bruce
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society of Hematology 2011
Gaiak:
Immunobiology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3123024/
https://ncbi.nlm.nih.gov/pubmed/21551232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-01-329607
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