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Disruption of MyD88 signaling suppresses hemophagocytic lymphohistiocytosis in mice
Hemophagocytic lymphohistiocytosis (HLH) is a rare inflammatory disorder with a poor prognosis for affected individuals. To find a means of suppressing the clinical phenotype, we investigated the cellular and molecular mechanisms leading to HLH in Unc13d(jinx/jinx) mice, in which cytolytic function...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society of Hematology
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3123024/ https://ncbi.nlm.nih.gov/pubmed/21551232 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-01-329607 |
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