The diverse role of the PPARγ coactivator 1 family of transcriptional coactivators in cancer

Por Girnun, Geoffrey D.
Publicado em 2012

Analysis of sphingolipids, sterols, and phospholipids in human pathogenic Cryptococcus strains

Por Singh, Ashutosh, MacKenzie, Andrew, Girnun, Geoffrey, Del Poeta, Maurizio
Publicado no J Lipid Res (2017)

Hic-5 regulates an epithelial program mediated by PPARγ

Por Drori, Stavit, Girnun, Geoffrey D., Tou, Liqiang, Szwaya, Jeffrey D., Mueller, Elisabetta, Kia, Xia, Shivdasani, Ramesh A., Spiegelman, Bruce M.
Publicado em 2005

Synergy between PPARγ Ligands and Platinum-Based Drugs in Cancer

Por Girnun, Geoffrey D., Naseri, Elnaz, Vafai, Scott B., Qu, Lishu, Szwaya, Jeffrey D., Bronson, Roderick, Alberta, John A., Spiegelman, Bruce M.
Publicado em 2007

Rapid Detection of an ABT-737-Sensitive Primed for Death State in Cells Using Microplate-Based Respirometry

Por Clerc, Pascaline, Carey, Gregory B., Mehrabian, Zara, Wei, Michael, Hwang, Hyehyun, Girnun, Geoffrey D., Chen, Hegang, Martin, Stuart S., Polster, Brian M.
Publicado em 2012

N-Acetylfarnesylcysteine Is a Novel Class of Peroxisome Proliferator-activated Receptor γ Ligand with Partial and Full Agonist Activity in Vitro and in Vivo

Por Bhalla, Kavita, Hwang, Bor Jang, Choi, Jang Hyun, Dewi, Ruby, Ou, Lihui, Mclenithan, John, Twaddel, William, Pozharski, Edwin, Stock, Jeffry, Girnun, Geoffrey D.
Publicado em 2011

Metformin prevents liver tumorigenesis by inhibiting pathways driving hepatic lipogenesis

Por Bhalla, Kavita, Hwang, Bor Jang, Dewi, Ruby E., Twaddel, William, Goloubeva, Olga G., Wong, Kwok-Kin, Saxena, Neeraj K., Biswal, Shyam, Girnun, Geoffrey D.
Publicado em 2012

Liposomal Doxorubicin Increases Radiofrequency Ablation–induced Tumor Destruction by Increasing Cellular Oxidative and Nitrative Stress and Accelerating Apoptotic Pathways(1)

Por Solazzo, Stephanie A., Ahmed, Muneeb, Schor-Bardach, Rachel, Yang, Wei, Girnun, Geoffrey D., Rahmanuddin, Syed, Levchenko, Tatyana, Signoretti, Sabina, Spitz, Douglas R., Torchilin, Vladimir, Goldberg, S. Nahum
Publicado em 2010

PGC1α promotes tumor growth by inducing gene expression programs supporting lipogenesis

Por Bhalla, Kavita, Hwang, Bor Jang, Dewi, Ruby E., Ou, Lihui, Twaddel, William, Fang, Hong-bin, Vafai, Scott B., Vazquez, Francesca, Puigserver, Pere, Boros, Laszlo, Girnun, Geoffrey
Publicado em 2011

Cyclin D1 Represses Gluconeogenesis via Inhibition of the Transcriptional Coactivator PGC1α

Por Bhalla, Kavita, Liu, Wan-Ju, Thompson, Keyata, Anders, Lars, Devarakonda, Srikripa, Dewi, Ruby, Buckley, Stephanie, Hwang, Bor-Jang, Polster, Brian, Dorsey, Susan G., Sun, Yezhou, Sicinski, Piotr, Girnun, Geoffrey D.
Publicado no Diabetes (2014)

APC-dependent suppression of colon carcinogenesis by PPARγ

Por Girnun, Geoffrey D., Smith, Wendy M., Drori, Stavit, Sarraf, Pasha, Mueller, Elisabetta, Eng, Charis, Nambiar, Prashant, Rosenberg, Daniel W., Bronson, Roderick T., Edelmann, Winfried, Kucherlapati, Raju, Gonzalez, Frank J., Spiegelman, Bruce M.
Publicado em 2002

The RUNX2 Transcription Factor Negatively Regulates SIRT6 Expression to Alter Glucose Metabolism in Breast Cancer Cells

Por Choe, Moran, Brusgard, Jessica L., Chumsri, Sara, Bhandary, Lekhana, Zhao, X. Frank, Lu, Song, Goloubeva, Olga G., Polster, Brian M., Fiskum, Gary M., Girnun, Geoffrey D., Kim, Myoung Sook, Passaniti, Antonino
Publicado no J Cell Biochem (2015)

Transcription factor NRF2 regulates miR-1 and miR-206 to drive tumorigenesis

Por Singh, Anju, Happel, Christine, Manna, Soumen K., Acquaah-Mensah, George, Carrerero, Julian, Kumar, Sarvesh, Nasipuri, Poonam, Krausz, Kristopher W., Wakabayashi, Nobunao, Dewi, Ruby, Boros, Laszlo G., Gonzalez, Frank J., Gabrielson, Edward, Wong, Kwok K., Girnun, Geoffrey, Biswal, Shyam
Publicado em 2013

Regression of Drug-Resistant Lung Cancer by the Combination of Rosiglitazone and Carboplatin

Por Girnun, Geoffrey D., Chen, Liang, Silvaggi, Jessica, Drapkin, Ronny, Chirieac, Lucian R., Padera, Robert F., Upadhyay, Rabi, Vafai, Scott B., Weissleder, Ralph, Mahmood, Umar, Naseri, Elnaz, Buckley, Stephanie, Li, Danan, Force, Jeremy, McNamara, Kate, Demetri, George, Spiegelman, Bruce M., Wong, Kwok-Kin
Publicado em 2008

Oncogenic Myc induces expression of glutamine synthetase through promoter demethylation

Por Bott, Alex J., Peng, I-Chen, Fan, Yongjun, Faubert, Brandon, Zhao, Lu, Li, Jinyu, Neidler, Sarah, Sun, Yu, Jaber, Nadia, Krokowski, Dawid, Lu, Wenyun, Pan, Ji-An, Powers, Scott, Rabinowitz, Joshua, Hatzoglou, Maria, Murphy, Daniel J., Jones, Russell, Wu, Song, Girnun, Geoffrey, Zong, Wei-Xing
Publicado no Cell Metab (2015)

PEPCK coordinates the regulation of central carbon metabolism to promote cancer cell growth

Por Montal, Emily, Dewi, Ruby, Bhalla, Kavita, Ou, Lihui, Hwang, Bor Jang, Ropell, Ashley, Gordon, Chris, Liu, Wan-Ju, DeBerardinis, Ralph J., Sudderth, Jessica, Twaddel, William, Boros, Lazlo, Shroyer, Kenneth, Duraisamy, Sekhar, Drapkin, Ronny, Powers, R. Scott, Rohde, Jason M., Boxer, Matthew B., Wong, Kwok-Kin, Girnun, Geoffrey D
Publicado no Mol Cell (2015)