Cyclin D1 Represses Gluconeogenesis via Inhibition of the Transcriptional Coactivator PGC1α

Hepatic gluconeogenesis is crucial to maintain normal blood glucose during periods of nutrient deprivation. Gluconeogenesis is controlled at multiple levels by a variety of signal transduction and transcriptional pathways. However, dysregulation of these pathways leads to hyperglycemia and type 2 di...

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Detalhes bibliográficos
Publicado no:Diabetes
Principais autores: Bhalla, Kavita, Liu, Wan-Ju, Thompson, Keyata, Anders, Lars, Devarakonda, Srikripa, Dewi, Ruby, Buckley, Stephanie, Hwang, Bor-Jang, Polster, Brian, Dorsey, Susan G., Sun, Yezhou, Sicinski, Piotr, Girnun, Geoffrey D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2014
Assuntos:
Metabolism
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4392904/
https://ncbi.nlm.nih.gov/pubmed/24947365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db13-1283
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