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PGC1α promotes tumor growth by inducing gene expression programs supporting lipogenesis

Despite the role of aerobic glycolysis in cancer, recent studies highlight the importance of the mitochondria and biosynthetic pathways as well. PPARγ coactivator 1α (PGC1α) is a key transcriptional regulator of several metabolic pathways including oxidative metabolism and lipogenesis. Initial studi...

詳細記述

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書誌詳細
主要な著者: Bhalla, Kavita, Hwang, Bor Jang, Dewi, Ruby E., Ou, Lihui, Twaddel, William, Fang, Hong-bin, Vafai, Scott B., Vazquez, Francesca, Puigserver, Pere, Boros, Laszlo, Girnun, Geoffrey
フォーマット: Artigo
言語:Inglês
出版事項: 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3282487/
https://ncbi.nlm.nih.gov/pubmed/21914785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-1011
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