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Metformin prevents liver tumorigenesis by inhibiting pathways driving hepatic lipogenesis

A number of factors have been identified that increase the risk of HCC. Recently it has become appreciated that type II diabetes increases the risk of developing HCC. This represents a patient population that can be identified and targeted for cancer prevention. The biguanide metformin is a first li...

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Detalhes bibliográficos
Main Authors: Bhalla, Kavita, Hwang, Bor Jang, Dewi, Ruby E., Twaddel, William, Goloubeva, Olga G., Wong, Kwok-Kin, Saxena, Neeraj K., Biswal, Shyam, Girnun, Geoffrey D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3324649/
https://ncbi.nlm.nih.gov/pubmed/22467080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-11-0228
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