Transcription factor NRF2 regulates miR-1 and miR-206 to drive tumorigenesis

The mechanisms by which deregulated nuclear factor erythroid-2–related factor 2 (NRF2) and kelch-like ECH-associated protein 1 (KEAP1) signaling promote cellular proliferation and tumorigenesis are poorly understood. Using an integrated genomics and (13)C-based targeted tracer fate association (TTFA...

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Detalhes bibliográficos
Main Authors: Singh, Anju, Happel, Christine, Manna, Soumen K., Acquaah-Mensah, George, Carrerero, Julian, Kumar, Sarvesh, Nasipuri, Poonam, Krausz, Kristopher W., Wakabayashi, Nobunao, Dewi, Ruby, Boros, Laszlo G., Gonzalez, Frank J., Gabrielson, Edward, Wong, Kwok K., Girnun, Geoffrey, Biswal, Shyam
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3696551/
https://ncbi.nlm.nih.gov/pubmed/23921124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI66353
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