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Synergy between PPARγ Ligands and Platinum-Based Drugs in Cancer

PPARγ is a member of the nuclear receptor family for which agonist ligands have antigrowth effects. However, clinical studies using PPARγ ligands as a monotherapy failed to show a beneficial effect. Here we have studied the effects of PPARγ activation with chemotherapeutic agents in current use for...

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Détails bibliographiques
Auteurs principaux: Girnun, Geoffrey D., Naseri, Elnaz, Vafai, Scott B., Qu, Lishu, Szwaya, Jeffrey D., Bronson, Roderick, Alberta, John A., Spiegelman, Bruce M.
Format: Artigo
Langue:Inglês
Publié: 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2564847/
https://ncbi.nlm.nih.gov/pubmed/17482130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2007.02.025
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