Quantitative Multiplexed Analysis of ErbB Family Co-expression for Primary Breast Cancer Prognosis in a Large Retrospective Cohort

Por Giltnane, Jennifer M., Moeder, Christopher B., Camp, Robert L., Rimm, David L.
Publicado em 2009

Expression patterns and prognostic value of Bag-1 and Bcl-2 in breast cancer

Por Nadler, Yasmine, Camp, Robert L, Giltnane, Jennifer M, Moeder, Christopher, Rimm, David L, Kluger, Harriet M, Kluger, Yuval
Publicado em 2008

The ERα coactivator, HER4/4ICD, regulates progesterone receptor expression in normal and malignant breast epithelium

Por Rokicki, Jerzy, Das, Partha M, Giltnane, Jennifer M, Wansbury, Olivia, Rimm, David L, Howard, Beatrice A, Jones, Frank E
Publicado em 2010

Analytic Variability in Immunohistochemistry Biomarker Studies

Por Anagnostou, Valsamo K., Welsh, Allison W., Giltnane, Jennifer M., Siddiqui, Summar, Liceaga, Camil, Gustavson, Mark, Syrigos, Konstantinos N., Reiter, Jill L., Rimm, David L.
Publicado em 2010

PDGFRB-rearranged T-lymphoblastic leukemia/lymphoma occurring with myeloid neoplasms: the missing link supporting a stem cell origin

Por Ondrejka, Sarah L., Jegalian, Armin G., Kim, Annette S., Chabot-Richards, Devon S., Giltnane, Jennifer, Czuchlewski, David R., Shetty, Shashirekha, Sekeres, Mikkael A, Yenamandra, Ashwini, Head, David, Jagasia, Madan, Hsi, Eric D.
Publicado no Haematologica (2014)

Single-cell dynamics determines response to CDK4/6 inhibition in triple negative breast cancer

Por Asghar, Uzma S., Barr, Alexis R., Cutts, Ros, Beaney, Matthew, Babina, Irina, Sampath, Deepak, Giltnane, Jennifer, Lacap, Jennifer Arca, Crocker, Lisa, Young, Amy, Pearson, Alex, Herrera-Abreu, Maria Teresa, Bakal, Chris, Turner, Nicholas C.
Publicado no Clin Cancer Res (2017)

Kinome wide functional screen identifies role of Polo-like kinase 1 (PLK1) in hormone-independent, ER-positive breast cancer

Por Bhola, Neil, Jansen, Valerie M., Bafna, Sangeeta, Giltnane, Jennifer M., Balko, Justin M., Estrada, Mónica V., Meszoely, Ingrid, Mayer, Ingrid, Abramson, Vandana, Ye, Fei, Sanders, Melinda, Dugger, Teresa C., Van Allen, Eliezer, Arteaga, Carlos L.
Publicado no Cancer Res (2014)

NRG1 is a critical regulator of differentiation in TP63-driven squamous cell carcinoma

Por Hegde, Ganapati V, de la Cruz, Cecile, Giltnane, Jennifer M, Crocker, Lisa, Venkatanarayan, Avinashnarayan, Schaefer, Gabriele, Dunlap, Debra, Hoeck, Joerg D, Piskol, Robert, Gnad, Florian, Modrusan, Zora, de Sauvage, Frederic J, Siebel, Christian W, Jackson, Erica L
Publicado no eLife (2019)

MYC and MCL1 cooperatively promote chemotherapy-resistant breast cancer stem cells through regulation of mitochondrial oxidative phosphorylation

Por Lee, Kyung-min, Giltnane, Jennifer M., Balko, Justin M., Schwarz, Luis J., Guerrero-Zotano, Angel L., Hutchinson, Katherine E., Nixon, Mellissa J., Estrada, Mónica V., Sánchez, Violeta, Sanders, Melinda E., Lee, Taekyu, Gómez, Henry, Lluch, Ana, Pérez-Fidalgo, J. Alejandro, Wolf, Melissa Magdalene, Andrejeva, Gabriela, Rathmell, Jeffrey C., Fesik, Stephen W., Arteaga, Carlos L.
Publicado no Cell Metab (2017)

Triple negative breast cancers with amplification of JAK2 at the 9p24 loci demonstrate JAK2-specific dependence

Por Balko, Justin M., Schwarz, Luis J., Cook, Rebecca S., Estrada, Monica V., Giltnane, Jennifer M., Sanders, Melinda E., Sánchez, Violeta, Dean, Phillip T., Wang, Kai, Combs, Susan E., Hicks, Donna, Pinto, Joseph A., Landis, Melissa D., Chang, Jenny C., Doimi, Franco D., Gómez, Henry, Rimm, David L., Yelensky, Roman, Miller, Vincent A., Stephens, Phillip J., Arteaga, Carlos L.
Publicado no Sci Transl Med (2016)

Association of FGFR1 with ERα maintains ligand-independent ER transcription and mediates resistance to estrogen deprivation in ER+ breast cancer

Por Formisano, Luigi, Stauffer, Kimberly M., Young, Christian D., Bhola, Neil E., Guerrero, Angel L., Jansen, Valerie M., Estrada, Mónica Valeria, Hutchinson, Katherine E., Giltnane, Jennifer M., Schwarz, Luis J., Lu, Yao, Balko, Justin M., Deas, Olivier, Cairo, Stefano, Judde, Jean-Gabriel, Mayer, Ingrid A., Sanders, Melinda E., Dugger, Teresa C., Bianco, Roberto, Stricker, Thomas P., Arteaga, Carlos L.
Publicado no Clin Cancer Res (2017)

ER+ breast cancers resistant to prolonged neoadjuvant letrozole exhibit an E2F4 transcriptional program sensitive to CDK4/6 inhibitors

Por Guerrero-Zotano, Angel L., Stricker, Thomas P., Formisano, Luigi, Hutchinson, Katherine E., Stover, Daniel G., Lee, Kyung-min, Schwarz, Luis J., Giltnane, Jennifer M., Estrada, Valeria M., Jansen, Valerie M., Servetto, Alberto, Gavilá, Joaquín, Perez-Fidalgo, J. Alejandro, Lluch, Ana, Llombart, Antonio, Bayar, Mohamed A., Michiels, Stefan, André, Fabrice, Arnedos, Mónica, Guillem, Vicente, Ruiz, Amparo, Arteaga, Carlos L.
Publicado no Clin Cancer Res (2018)

Correction: ER(+) Breast Cancers Resistant to Prolonged Neoadjuvant Letrozole Exhibit an E2F4 Transcriptional Program Sensitive to CDK4/6 Inhibitors

Por Guerrero-Zotano, Angel L., Stricker, Thomas P., Formisano, Luigi, Hutchinson, Katherine E., Stover, Daniel G., Lee, Kyung-Min, Schwarz, Luis J., Giltnane, Jennifer M., Estrada, Monica V., Jansen, Valerie M., Servetto, Alberto, Gavilá, Joaquín, Perez-Fidalgo, J. Alejandro, Lluch, Ana, Llombart-Cussac, Antonio, Bayar, Mohamed Amine, Michiels, Stefan, André, Fabrice, Arnedos, Mόnica, Guillem, Vicente, Ruiz-Simon, Amparo, Arteaga, Carlos L.
Publicado no Clin Cancer Res (2019)

RAS/MAPK activation is associated with reduced tumor-infiltrating lymphocytes in triple-negative breast cancer: therapeutic cooperation between MEK and PD-1/PD-L1 immune checkpoint...

Por Loi, Sherene, Dushyanthen, Sathana, Beavis, Paul A, Salgado, Roberto, Denkert, Carsten, Savas, Peter, Combs, Susan, Rimm, David L., Giltnane, Jennifer M., Estrada, Monica V., Sánchez, Violeta, Sanders, Melinda E., Cook, Rebecca S., Pilkinton, Mark A., Mallal, Simon A., Wang, Kai, Miller, Vincent A., Stephens, Phil J., Yelensky, Roman, Doimi, Franco D., Gómez, Henry, Ryzhov, Sergey V., Darcy, Phillip K., Arteaga, Carlos L., Balko, Justin M.
Publicado no Clin Cancer Res (2015)

Molecular profiling of the residual disease of triple-negative breast cancers after neoadjuvant chemotherapy identifies actionable therapeutic targets

Por Balko, Justin M., Giltnane, Jennifer M., Wang, Kai, Schwarz, Luis J., Young, Christian D., Cook, Rebecca S., Owens, Phillip, Sanders, Melinda E., Kuba, Maria G., Sánchez, Violeta, Kurupi, Richard, Moore, Preston D., Pinto, Joseph A., Doimi, Franco D., Gómez, Henry, Horiuchi, Dai, Goga, Andrei, Lehmann, Brian D., Bauer, Joshua A., Pietenpol, Jennifer A., Ross, Jeffrey S., Palmer, Gary A., Yelensky, Roman, Cronin, Maureen, Miller, Vincent A., Stephens, Phillip J., Arteaga, Carlos L.
Publicado em 2013

Emergence of constitutively active estrogen receptor-α mutations in pretreated advanced estrogen receptor positive breast cancer

Por Jeselsohn, Rinath, Yelensky, Roman, Buchwalter, Gilles, Frampton, Garrett, Meric-Bernstam, Funda, Gonzalez-Angulo, Ana Maria, Ferrer-Lozano, Jaime, Perez-Fidalgo, Jose A., Cristofanilli, Massimo, Gómez, Henry, Arteaga, Carlos L., Giltnane, Jennifer, Balko, Justin M., Cronin, Maureen T, Jarosz, Mirna, Sun, James, Hawryluk, Matthew, Lipson, Doron, Otto, Geoff, Ross, Jeffrey S, Dvir, Addie, Soussan-Gutman, Lior, Wolf, Ido, Rubinek, Tamar, Gilmore, Lauren, Schnitt, Stuart, Come, Steven E., Pusztai, Lajos, Stephens, Philip, Brown, Myles, Miller, Vincent A.
Publicado em 2014

TGF-β attenuates tumour response to PD-L1 blockade by contributing to exclusion of T cells

Por Mariathasan, Sanjeev, Turley, Shannon J., Nickles, Dorothee, Castiglioni, Alessandra, Yuen, Kobe, Wang, Yulei, Kadel, Edward E., Koeppen, Hartmut, Astarita, Jillian L., Cubas, Rafael, Jhunjhunwala, Suchit, Banchereau, Romain, Yang, Yagai, Guan, Yinghui, Chalouni, Cecile, Ziai, James, Şenbabaoğlu, Yasin, Santoro, Stephen, Sheinson, Daniel, Hung, Jeffrey, Giltnane, Jennifer M., Pierce, Andrew K., Mesh, Kathryn, Lianoglou, Steve, Riegler, Johannes, Carano, Richard A. D., Eriksson, Pontus, Hoglund, Mattias, Somarriba, Loan, Halligan, Daniel L., van der Heijden, Michiel, Loriot, Yohann, Rosenberg, Jonathan E., Fong, Lawrence, Mellman, Ira, Chen, Daniel S., Green, Marjorie, Derleth, Christina, Fine, Gregg D., Hegde, Priti S., Bourgon, Richard, Powles, Thomas
Publicado no Nature (2018)

The selective estrogen receptor downregulator GDC-0810 is efficacious in diverse models of ER+ breast cancer

Por Joseph, James D, Darimont, Beatrice, Zhou, Wei, Arrazate, Alfonso, Young, Amy, Ingalla, Ellen, Walter, Kimberly, Blake, Robert A, Nonomiya, Jim, Guan, Zhengyu, Kategaya, Lorna, Govek, Steven P, Lai, Andiliy G, Kahraman, Mehmet, Brigham, Dan, Sensintaffar, John, Lu, Nhin, Shao, Gang, Qian, Jing, Grillot, Kate, Moon, Michael, Prudente, Rene, Bischoff, Eric, Lee, Kyoung-Jin, Bonnefous, Celine, Douglas, Karensa L, Julien, Jackaline D, Nagasawa, Johnny Y, Aparicio, Anna, Kaufman, Josh, Haley, Benjamin, Giltnane, Jennifer M, Wertz, Ingrid E, Lackner, Mark R, Nannini, Michelle A, Sampath, Deepak, Schwarz, Luis, Manning, Henry Charles, Tantawy, Mohammed Noor, Arteaga, Carlos L, Heyman, Richard A, Rix, Peter J, Friedman, Lori, Smith, Nicholas D, Metcalfe, Ciara, Hager, Jeffrey H
Publicado no eLife (2016)

Correction: The selective estrogen receptor downregulator GDC-0810 is efficacious in diverse models of ER+ breast cancer

Por Joseph, James D, Darimont, Beatrice, Zhou, Wei, Arrazate, Alfonso, Young, Amy, Ingalla, Ellen, Walter, Kimberly, Blake, Robert A, Nonomiya, Jim, Guan, Zhengyu, Kategaya, Lorna, Govek, Steven P, Lai, Andiliy G, Kahraman, Mehmet, Brigham, Dan, Sensintaffar, John, Lu, Nhin, Shao, Gang, Qian, Jing, Grillot, Kate, Moon, Michael, Prudente, Rene, Bischoff, Eric, Lee, Kyoung-Jin, Bonnefous, Celine, Douglas, Karensa L, Julien, Jackaline D, Nagasawa, Johnny Y, Aparicio, Anna, Kaufman, Josh, Haley, Benjamin, Giltnane, Jennifer M, Wertz, Ingrid E, Lackner, Mark R, Nannini, Michelle A, Sampath, Deepak, Schwarz, Luis, Manning, Henry Charles, Tantawy, Mohammed Noor, Arteaga, Carlos L, Heyman, Richard A, Rix, Peter J, Friedman, Lori, Smith, Nicholas D, Metcalfe, Ciara, Hager, Jeffrey H
Publicado no eLife (2019)

Assessing tumor infiltrating lymphocytes in solid tumors: a practical review for pathologists and proposal for a standardized method from the International Immuno-Oncology Biomarke...

Por Hendry, Shona, Salgado, Roberto, Gevaert, Thomas, Russell, Prudence A., John, Tom, Thapa, Bibhusal, Christie, Michael, van de Vijver, Koen, Estrada, M. Valeria, Gonzalez-Ericsson, Paula I., Sanders, Melinda, Solomon, Benjamin, Solinas, Cinzia, Van den Eynden, Gert GGM, Allory, Yves, Preusser, Matthias, Hainfellner, Johannes, Pruneri, Giancarlo, Vingiani, Andrea, Demaria, Sandra, Symmans, Fraser, Nuciforo, Paolo, Comerma, Laura, Thompson, E. Aubrey, Lakhani, Sunil, Kim, Seong-Rim, Schnitt, Stuart, Colpaert, Cecile, Sotiriou, Christos, Scherer, Stefan J., Ignatiadis, Michail, Badve, Sunil, Pierce, Robert H., Viale, Giuseppe, Sirtaine, Nicolas, Penault-Llorca, Frederique, Sugie, Tomohagu, Fineberg, Susan, Paik, Soonmyung, Srinivasan, Ashok, Richardson, Andrea, Wang, Yihong, Chmielik, Ewa, Brock, Jane, Johnson, Douglas B., Balko, Justin, Wienert, Stephan, Bossuyt, Veerle, Michiels, Stefan, Ternes, Nils, Burchardi, Nicole, Luen, Stephen J., Savas, Peter, Klauschen, Frederick, Watson, Peter H., Nelson, Brad H., Criscitiello, Carmen, O’Toole, Sandra, Larsimont, Denis, de Wind, Roland, Curigliano, Giuseppe, André, Fabrice, Lacroix-Triki, Magali, van de Vijver, Mark, Rojo, Federico, Floris, Giuseppe, Bedri, Shahinaz, Sparano, Joseph, Rimm, David, Nielsen, Torsten, Kos, Zuzana, Hewitt, Stephen, Singh, Baljit, Farshid, Gelareh, Loibl, Sibylle, Allison, Kimberly H., Tung, Nadine, Adams, Sylvia, Willard-Gallo, Karen, Horlings, Hugo M., Gandhi, Leena, Moreira, Andre, Hirsch, Fred, Dieci, Maria Vittoria, Urbanowicz, Maria, Brcic, Iva, Korski, Konstanty, Gaire, Fabien, Koeppen, Hartmut, Lo, Amy, Giltnane, Jennifer, Ziai, James, Rebelatto, Marlon C., Steele, Keith E., Zha, Jiping, Emancipator, Kenneth, Juco, Jonathan W., Denkert, Carsten, Reis-Filho, Jorge, Loi, Sherene, Fox, Stephen B.
Publicado no Adv Anat Pathol (2017)