Emergence of constitutively active estrogen receptor-α mutations in pretreated advanced estrogen receptor positive breast cancer

PURPOSE: We undertook this study to determine the prevalence of estrogen receptor (ER) α (ESR1) mutations throughout the natural history of hormone dependent breast cancer and to delineate the functional roles of the most commonly detected alterations. EXPERIMENTAL DESIGN: We studied a total of 249...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Jeselsohn, Rinath, Yelensky, Roman, Buchwalter, Gilles, Frampton, Garrett, Meric-Bernstam, Funda, Gonzalez-Angulo, Ana Maria, Ferrer-Lozano, Jaime, Perez-Fidalgo, Jose A., Cristofanilli, Massimo, Gómez, Henry, Arteaga, Carlos L., Giltnane, Jennifer, Balko, Justin M., Cronin, Maureen T, Jarosz, Mirna, Sun, James, Hawryluk, Matthew, Lipson, Doron, Otto, Geoff, Ross, Jeffrey S, Dvir, Addie, Soussan-Gutman, Lior, Wolf, Ido, Rubinek, Tamar, Gilmore, Lauren, Schnitt, Stuart, Come, Steven E., Pusztai, Lajos, Stephens, Philip, Brown, Myles, Miller, Vincent A.
التنسيق: Artigo
اللغة:Inglês
منشور في: 2014
الموضوعات:
Article
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC3998833/
https://ncbi.nlm.nih.gov/pubmed/24398047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-13-2332
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