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Are We Ready to Use ESR1 Mutations in Clinical Practice?
The recurrent ligand-binding domain ESR1 mutations are an important mechanism of endocrine resistance in estrogen receptor-positive (ER+) metastatic breast cancer. These mutations evolve under the selective pressure of endocrine treatments and are rarely found in treatment-naïve ER+ breast cancers....
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| Pubblicato in: | Breast Care (Basel) |
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| Autore principale: | |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
S. Karger GmbH
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5704725/ https://ncbi.nlm.nih.gov/pubmed/29234250 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000481428 |
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