Inhibitors of Protein-Protein Interactions (PPIs): An Analysis of Scaffold Choices and Buried Surface Area

av Ran, Xu, Gestwicki, Jason E.
I publikationen Curr Opin Chem Biol (2018)

Inhibitors and chemical probes for molecular chaperone networks

av Gestwicki, Jason E., Shao, Hao
I publikationen J Biol Chem (2019)

Neutral analogs of the heat shock protein 70 (Hsp70) inhibitor, JG-98

av Shao, Hao, Gestwicki, Jason E.
I publikationen Bioorg Med Chem Lett (2020)

Enantioselective Organocatalytic Hantzsch Synthesis of Polyhydroquinolines

av Evans, Christopher G., Gestwicki, Jason E.
Publicerad 2009

Insight into Amyloid Structure Using Chemical Probes

av Reinke, Ashley A., Gestwicki, Jason E.
Publicerad 2011

Expanding the Number of “Druggable” Targets: Non-Enzymes and Protein-Protein Interactions

av Makley, Leah N., Gestwicki, Jason E.
Publicerad 2013

Features of Protein-Protein Interactions that Translate into Potent Inhibitors: Topology, Surface Area and Affinity

av Smith, Matthew C., Gestwicki, Jason E.
Publicerad 2012

Binding of Human Nucleotide Exchange Factors to Heat Shock Protein 70 (Hsp70) Generates Functionally Distinct Complexes in Vitro

av Rauch, Jennifer N., Gestwicki, Jason E.
Publicerad 2014

Peptidyl-Proline Isomerases (PPIases): Targets for Natural Products and Natural Product-Inspired Compounds: Miniperspective

av Dunyak, Bryan M., Gestwicki, Jason E.
I publikationen J Med Chem (2016)

Retraction of “Enantioselective Organocatalytic Hantzsch Synthesis of Polyhydroquinolines”

av Evans, Christopher G., Gestwicki, Jason E.
I publikationen Org Lett (2021)

Pharmacological Targeting of the Hsp70 Chaperone

av Patury, Srikanth, Miyata, Yoshinari, Gestwicki, Jason E.
Publicerad 2009

Synthetic lethal interactions in yeast reveal functional roles of J protein co-chaperones

av Gillies, Anne, Taylor, Rebecca, Gestwicki, Jason E.
Publicerad 2012

Backbone and methyl resonance assignments of the 42 kDa human Hsc70 nucleotide binding domain in the ADP state

av Zuiderweg, Erik R. P., Gestwicki, Jason E.
I publikationen Biomol NMR Assign (2016)

Aim for the Core: Suitability of the ubiquitin-independent 20S proteasome as a drug target in neurodegeneration

av Opoku-Nsiah, Kwadwo A., Gestwicki, Jason E.
I publikationen Transl Res (2018)

Heat Shock Protein 70 (Hsp70) as an Emerging Drug Target

av Evans, Christopher G., Chang, Lyra, Gestwicki, Jason E.
Publicerad 2010

Therapeutic Strategies for Restoring Tau Homeostasis

av Young, Zapporah T., Mok, Sue Ann, Gestwicki, Jason E.
I publikationen Cold Spring Harb Perspect Med (2018)

From Fuzzy to Function: The New Frontier of Protein–Protein Interactions

av Pricer, Rachel, Gestwicki, Jason E, Mapp, Anna K
I publikationen Acc Chem Res (2017)

Luminescence Complementation Assay for Measurement of Binding to Protein C-Termini in Live Cells

av Nadel, Cory M., Ran, Xu, Gestwicki, Jason E.
I publikationen Anal Biochem (2020)

A Chemical Screening Approach Reveals that Indole Flourescence is Quenched by Pre-Fibrillar But Not Fibrillar Amyloid-β

av Reinke, Ashley A., Seh, Han Yiau, Gestwicki, Jason E.
Publicerad 2009

Synthetic Multivalent Ligands as Probes of Signal Transduction

av Kiessling, Laura L., Gestwicki, Jason E., Strong, Laura E.
Publicerad 2006