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From Fuzzy to Function: The New Frontier of Protein–Protein Interactions

Conformationally heterogenous or “fuzzy” proteins have often been described as lacking specificity in binding and in function. The activation domains, for example, of transcriptional activators were labeled as negative noodles, with little structure or specificity. However, emerging data illustrates...

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Detalhes bibliográficos
Publicado no:Acc Chem Res
Main Authors: Pricer, Rachel, Gestwicki, Jason E, Mapp, Anna K
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5786153/
https://ncbi.nlm.nih.gov/pubmed/28945413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.accounts.6b00565
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