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Direct and Propagated Effects of Small Molecules on Protein–Protein Interaction Networks

Networks of protein–protein interactions (PPIs) link all aspects of cellular biology. Dysfunction in the assembly or dynamics of PPI networks is a hallmark of human disease, and as such, there is growing interest in the discovery of small molecules that either promote or inhibit PPIs. PPIs were once...

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Detalhes bibliográficos
Publicado no:Front Bioeng Biotechnol
Main Authors: Cesa, Laura C., Mapp, Anna K., Gestwicki, Jason E.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4547496/
https://ncbi.nlm.nih.gov/pubmed/26380257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2015.00119
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