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Binding of Human Nucleotide Exchange Factors to Heat Shock Protein 70 (Hsp70) Generates Functionally Distinct Complexes in Vitro

Proteins with Bcl2-associated anthanogene (BAG) domains act as nucleotide exchange factors (NEFs) for the molecular chaperone heat shock protein 70 (Hsp70). There are six BAG family NEFs in humans, and each is thought to link Hsp70 to a distinct cellular pathway. However, little is known about how t...

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Detalhes bibliográficos
Main Authors: Rauch, Jennifer N., Gestwicki, Jason E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3894324/
https://ncbi.nlm.nih.gov/pubmed/24318877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.521997
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