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Binding of Human Nucleotide Exchange Factors to Heat Shock Protein 70 (Hsp70) Generates Functionally Distinct Complexes in Vitro

Proteins with Bcl2-associated anthanogene (BAG) domains act as nucleotide exchange factors (NEFs) for the molecular chaperone heat shock protein 70 (Hsp70). There are six BAG family NEFs in humans, and each is thought to link Hsp70 to a distinct cellular pathway. However, little is known about how t...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Rauch, Jennifer N., Gestwicki, Jason E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3894324/
https://ncbi.nlm.nih.gov/pubmed/24318877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.521997
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