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Enantioselective Organocatalytic Hantzsch Synthesis of Polyhydroquinolines

[Image: see text] The four component Hantzsch reaction provides access to pharmaceutically important dihydropyridines. To expand the utility of this method, we have developed a route under organocatalytic conditions with good yields and excellent ee's. Through catalyst screening, we found that...

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Detalhes bibliográficos
Main Authors: Evans, Christopher G., Gestwicki, Jason E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2727599/
https://ncbi.nlm.nih.gov/pubmed/19527003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol901114f
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