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Organocatalytic Highly Enantioselective Synthesis of Secondary α-Hydroxyphosphonates

[Image: see text] The first organocatalytic cross aldol reaction of ketones and diethyl formylphosphonate hydrate has been realized by using readily available L-prolinamide as the catalyst. Secondary α-hydroxyphosphonates have been synthesized in high enantioselective (up to >99% ee) and good dia...

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Detalhes bibliográficos
Principais autores: Dodda, Rajasekhar, Cong-Gui, Zhao
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2525621/
https://ncbi.nlm.nih.gov/pubmed/17020334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol062005s
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