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Organocatalytic Enantioselective Synthesis of α-Hydroxy Phosphonates

[Image: see text] Tertiary α-hydroxy phosphonates have been synthesized in good yields and high enantiomeric purity (up to 99% ee) through a novel L-proline-catalyzed cross aldol reaction of α-keto phosphonates and ketones.

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Detalhes bibliográficos
Main Authors: Samanta, Sampak, Zhao, Cong-Gui
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2535926/
https://ncbi.nlm.nih.gov/pubmed/16756289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja062091r
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