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Organocatalytic Enantioselective Synthesis of Both Diastereomers of α-Hydroxyphosphinates

Racemic α-acylphosphinates and formylphosphinate hydrate were used directly as the substrates in a proline derivative-catalyzed cross aldol reaction with ketones. Because of the preexisting the phosphorus stereogenic center, a mixture of two diastereomers of the corresponding α-hydroxyphosphinates w...

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Detalhes bibliográficos
Main Authors: Samanta, Sampak, Perera, Sandun, Zhao, Cong-Gui
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2821456/
https://ncbi.nlm.nih.gov/pubmed/20085234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo9022099
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