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Organocatalytic Enantioselective Olefin Aminofluorination

[Image: see text] Chiral β-fluoroamines are increasingly prevalent in medicinal compounds, but there are few efficient methods to access them from achiral starting materials. To address this, a multi-component organocascade reaction was developed in which chiral α-fluoro-β-amino aldehydes were gener...

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Detalhes bibliográficos
Main Authors: Appayee, Chandrakumar, Brenner-Moyer, Stacey E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2946328/
https://ncbi.nlm.nih.gov/pubmed/20575576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol101167z
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