Inhibitors of Protein-Protein Interactions (PPIs): An Analysis of Scaffold Choices and Buried Surface Area

Autor Ran, Xu, Gestwicki, Jason E.
Vydáno v Curr Opin Chem Biol (2018)

Inhibitors and chemical probes for molecular chaperone networks

Autor Gestwicki, Jason E., Shao, Hao
Vydáno v J Biol Chem (2019)

Neutral analogs of the heat shock protein 70 (Hsp70) inhibitor, JG-98

Autor Shao, Hao, Gestwicki, Jason E.
Vydáno v Bioorg Med Chem Lett (2020)

Enantioselective Organocatalytic Hantzsch Synthesis of Polyhydroquinolines

Autor Evans, Christopher G., Gestwicki, Jason E.
Vydáno 2009

Insight into Amyloid Structure Using Chemical Probes

Autor Reinke, Ashley A., Gestwicki, Jason E.
Vydáno 2011

Expanding the Number of “Druggable” Targets: Non-Enzymes and Protein-Protein Interactions

Autor Makley, Leah N., Gestwicki, Jason E.
Vydáno 2013

Features of Protein-Protein Interactions that Translate into Potent Inhibitors: Topology, Surface Area and Affinity

Autor Smith, Matthew C., Gestwicki, Jason E.
Vydáno 2012

Binding of Human Nucleotide Exchange Factors to Heat Shock Protein 70 (Hsp70) Generates Functionally Distinct Complexes in Vitro

Autor Rauch, Jennifer N., Gestwicki, Jason E.
Vydáno 2014

Peptidyl-Proline Isomerases (PPIases): Targets for Natural Products and Natural Product-Inspired Compounds: Miniperspective

Autor Dunyak, Bryan M., Gestwicki, Jason E.
Vydáno v J Med Chem (2016)

Retraction of “Enantioselective Organocatalytic Hantzsch Synthesis of Polyhydroquinolines”

Autor Evans, Christopher G., Gestwicki, Jason E.
Vydáno v Org Lett (2021)

Pharmacological Targeting of the Hsp70 Chaperone

Autor Patury, Srikanth, Miyata, Yoshinari, Gestwicki, Jason E.
Vydáno 2009

Synthetic lethal interactions in yeast reveal functional roles of J protein co-chaperones

Autor Gillies, Anne, Taylor, Rebecca, Gestwicki, Jason E.
Vydáno 2012

Backbone and methyl resonance assignments of the 42 kDa human Hsc70 nucleotide binding domain in the ADP state

Autor Zuiderweg, Erik R. P., Gestwicki, Jason E.
Vydáno v Biomol NMR Assign (2016)

Aim for the Core: Suitability of the ubiquitin-independent 20S proteasome as a drug target in neurodegeneration

Autor Opoku-Nsiah, Kwadwo A., Gestwicki, Jason E.
Vydáno v Transl Res (2018)

Heat Shock Protein 70 (Hsp70) as an Emerging Drug Target

Autor Evans, Christopher G., Chang, Lyra, Gestwicki, Jason E.
Vydáno 2010

Therapeutic Strategies for Restoring Tau Homeostasis

Autor Young, Zapporah T., Mok, Sue Ann, Gestwicki, Jason E.
Vydáno v Cold Spring Harb Perspect Med (2018)

From Fuzzy to Function: The New Frontier of Protein–Protein Interactions

Autor Pricer, Rachel, Gestwicki, Jason E, Mapp, Anna K
Vydáno v Acc Chem Res (2017)

Luminescence Complementation Assay for Measurement of Binding to Protein C-Termini in Live Cells

Autor Nadel, Cory M., Ran, Xu, Gestwicki, Jason E.
Vydáno v Anal Biochem (2020)

A Chemical Screening Approach Reveals that Indole Flourescence is Quenched by Pre-Fibrillar But Not Fibrillar Amyloid-β

Autor Reinke, Ashley A., Seh, Han Yiau, Gestwicki, Jason E.
Vydáno 2009

Synthetic Multivalent Ligands as Probes of Signal Transduction

Autor Kiessling, Laura L., Gestwicki, Jason E., Strong, Laura E.
Vydáno 2006