Inhibitors of Protein-Protein Interactions (PPIs): An Analysis of Scaffold Choices and Buried Surface Area

بواسطة Ran, Xu, Gestwicki, Jason E.
الحاوية / القاعدة Curr Opin Chem Biol (2018)

Inhibitors and chemical probes for molecular chaperone networks

بواسطة Gestwicki, Jason E., Shao, Hao
الحاوية / القاعدة J Biol Chem (2019)

Neutral analogs of the heat shock protein 70 (Hsp70) inhibitor, JG-98

بواسطة Shao, Hao, Gestwicki, Jason E.
الحاوية / القاعدة Bioorg Med Chem Lett (2020)

Enantioselective Organocatalytic Hantzsch Synthesis of Polyhydroquinolines

بواسطة Evans, Christopher G., Gestwicki, Jason E.
منشور في 2009

Insight into Amyloid Structure Using Chemical Probes

بواسطة Reinke, Ashley A., Gestwicki, Jason E.
منشور في 2011

Expanding the Number of “Druggable” Targets: Non-Enzymes and Protein-Protein Interactions

بواسطة Makley, Leah N., Gestwicki, Jason E.
منشور في 2013

Features of Protein-Protein Interactions that Translate into Potent Inhibitors: Topology, Surface Area and Affinity

بواسطة Smith, Matthew C., Gestwicki, Jason E.
منشور في 2012

Binding of Human Nucleotide Exchange Factors to Heat Shock Protein 70 (Hsp70) Generates Functionally Distinct Complexes in Vitro

بواسطة Rauch, Jennifer N., Gestwicki, Jason E.
منشور في 2014

Peptidyl-Proline Isomerases (PPIases): Targets for Natural Products and Natural Product-Inspired Compounds: Miniperspective

بواسطة Dunyak, Bryan M., Gestwicki, Jason E.
الحاوية / القاعدة J Med Chem (2016)

Retraction of “Enantioselective Organocatalytic Hantzsch Synthesis of Polyhydroquinolines”

بواسطة Evans, Christopher G., Gestwicki, Jason E.
الحاوية / القاعدة Org Lett (2021)

Pharmacological Targeting of the Hsp70 Chaperone

بواسطة Patury, Srikanth, Miyata, Yoshinari, Gestwicki, Jason E.
منشور في 2009

Synthetic lethal interactions in yeast reveal functional roles of J protein co-chaperones

بواسطة Gillies, Anne, Taylor, Rebecca, Gestwicki, Jason E.
منشور في 2012

Backbone and methyl resonance assignments of the 42 kDa human Hsc70 nucleotide binding domain in the ADP state

بواسطة Zuiderweg, Erik R. P., Gestwicki, Jason E.
الحاوية / القاعدة Biomol NMR Assign (2016)

Aim for the Core: Suitability of the ubiquitin-independent 20S proteasome as a drug target in neurodegeneration

بواسطة Opoku-Nsiah, Kwadwo A., Gestwicki, Jason E.
الحاوية / القاعدة Transl Res (2018)

Heat Shock Protein 70 (Hsp70) as an Emerging Drug Target

بواسطة Evans, Christopher G., Chang, Lyra, Gestwicki, Jason E.
منشور في 2010

Therapeutic Strategies for Restoring Tau Homeostasis

بواسطة Young, Zapporah T., Mok, Sue Ann, Gestwicki, Jason E.
الحاوية / القاعدة Cold Spring Harb Perspect Med (2018)

From Fuzzy to Function: The New Frontier of Protein–Protein Interactions

بواسطة Pricer, Rachel, Gestwicki, Jason E, Mapp, Anna K
الحاوية / القاعدة Acc Chem Res (2017)

Luminescence Complementation Assay for Measurement of Binding to Protein C-Termini in Live Cells

بواسطة Nadel, Cory M., Ran, Xu, Gestwicki, Jason E.
الحاوية / القاعدة Anal Biochem (2020)

A Chemical Screening Approach Reveals that Indole Flourescence is Quenched by Pre-Fibrillar But Not Fibrillar Amyloid-β

بواسطة Reinke, Ashley A., Seh, Han Yiau, Gestwicki, Jason E.
منشور في 2009

Synthetic Multivalent Ligands as Probes of Signal Transduction

بواسطة Kiessling, Laura L., Gestwicki, Jason E., Strong, Laura E.
منشور في 2006