Innovations for phase I dose-finding designs in pediatric oncology clinical trials

по Doussau, Adelaide, Geoerger, Birgit, Jiménez, Irene, Paoletti, Xavier
Опубликовано в: Contemp Clin Trials (2016)

Precision medicine in pediatric oncology

по Forrest, Suzanne J., Geoerger, Birgit, Janeway, Katherine A.
Опубликовано в: Curr Opin Pediatr (2018)

Relevance of Fusion Genes in Pediatric Cancers: Toward Precision Medicine

по Dupain, Célia, Harttrampf, Anne Catherine, Urbinati, Giorgia, Geoerger, Birgit, Massaad-Massade, Liliane
Опубликовано в: Mol Ther Nucleic Acids (2017)

Histone deacetylase inhibitor panobinostat induces antitumor activity in epithelioid sarcoma and rhabdoid tumor by growth factor receptor modulation

по Harttrampf, Anne Catherine, da Costa, Maria Eugenia Marques, Renoult, Aline, Daudigeos-Dubus, Estelle, Geoerger, Birgit
Опубликовано в: BMC Cancer (2021)

Discovery of New Fusion Transcripts in a Cohort of Pediatric Solid Cancers at Relapse and Relevance for Personalized Medicine

по Dupain, Célia, Harttrampf, Anne C., Boursin, Yannick, Lebeurrier, Manuel, Rondof, Windy, Robert-Siegwald, Guillaume, Khoueiry, Pierre, Geoerger, Birgit, Massaad-Massade, Liliane
Опубликовано в: Mol Ther (2019)

Phase II trial of temsirolimus in children with high-grade glioma, neuroblastoma and rhabdomyosarcoma()

по Geoerger, Birgit, Kieran, Mark W., Grupp, Stephan, Perek, Danuta, Clancy, Jill, Krygowski, Mizue, Ananthakrishnan, Revathi, Boni, Joseph P., Berkenblit, Anna, Spunt, Sheri L.
Опубликовано 2011

HG-44 EVALUATION OF ABT-414 IN CHILDREN WITH HIGH GRADE GLIOMA (HGG) AND DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG)

по van den Bent, Martin, Geoerger, Birgit, Golfinopoulos, Vassilis, Ansell, Peter, Bain, Earle, Looman, Jim, Xiong, Hao, Fischer, JuDee, Holen, Kyle, Hargrave, Darren
Опубликовано в: Neuro Oncol (2016)

A Perspective on Polo-Like Kinase-1 Inhibition for the Treatment of Rhabdomyosarcomas

по Gatz, Susanne A., Aladowicz, Ewa, Casanova, Michela, Chisholm, Julia C., Kearns, Pamela R., Fulda, Simone, Geoerger, Birgit, Schäfer, Beat W., Shipley, Janet M.
Опубликовано в: Front Oncol (2019)

LGG-46. TRAMETINIB THERAPY IN PEDIATRIC PATIENTS WITH LOW-GRADE GLIOMAS (LGG) WITH BRAF GENE FUSION; A DISEASE-SPECIFIC COHORT IN THE FIRST PEDIATRIC TESTING OF TRAMETINIB

по Bouffet, Eric, Kieran, Mark, Hargrave, Darren, Roberts, Stephen, Aerts, Isabelle, Broniscer, Alberto, Geoerger, Birgit, Dasgupta, Kohinoor, Tseng, Lillian, Russo, Mark, Mookerjee, Bijoyesh, Moertel, Christopher
Опубликовано в: Neuro Oncol (2018)

PDCT-02. EVALUATION OF DEPATUXIZUMAB MAFODOTIN (ABT-414) IN CHILDREN WITH HIGH GRADE GLIOMA (HGG) AND DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG)

по van den Bent, Martin, Geoerger, Birgit, Golfinopoulos, Vassilis, Ansell, Peter J, Bain, Earle, Looman, Jim, Xiong, Hao, Fischer, JuDee, Holen, Kyle D, Hargrave, Darren
Опубликовано в: Neuro Oncol (2017)

Establishment and characterization of in vivo orthotopic bioluminescent xenograft models from human osteosarcoma cell lines in Swiss nude and NSG mice

по Marques da Costa, Maria Eugenia, Daudigeos‐Dubus, Estelle, Gomez‐Brouchet, Anne, Bawa, Olivia, Rouffiac, Valerie, Serra, Massimo, Scotlandi, Katia, Santos, Conceição, Geoerger, Birgit, Gaspar, Nathalie
Опубликовано в: Cancer Med (2018)

In-Vitro and In-Vivo Establishment and Characterization of Bioluminescent Orthotopic Chemotherapy-Resistant Human Osteosarcoma Models in NSG Mice

по Marques da Costa, Maria Eugénia, Marchais, Antonin, Gomez-Brouchet, Anne, Job, Bastien, Assoun, Noémie, Daudigeos-Dubus, Estelle, Fromigué, Olivia, Santos, Conceição, Geoerger, Birgit, Gaspar, Nathalie
Опубликовано в: Cancers (Basel) (2019)

Regorafenib: Antitumor Activity upon Mono and Combination Therapy in Preclinical Pediatric Malignancy Models

по Daudigeos-Dubus, Estelle, Le Dret, Ludivine, Lanvers-Kaminsky, Claudia, Bawa, Olivia, Opolon, Paule, Vievard, Albane, Villa, Irène, Pagès, Mélanie, Bosq, Jacques, Vassal, Gilles, Zopf, Dieter, Geoerger, Birgit
Опубликовано в: PLoS One (2015)

Preliminary Efficacy of the Anti-Insulin–Like Growth Factor Type 1 Receptor Antibody Figitumumab in Patients With Refractory Ewing Sarcoma

по Juergens, Heribert, Daw, Najat C., Geoerger, Birgit, Ferrari, Stefano, Villarroel, Milena, Aerts, Isabelle, Whelan, Jeremy, Dirksen, Uta, Hixon, Mary L., Yin, Donghua, Wang, Tao, Green, Stephanie, Paccagnella, Luisa, Gualberto, Antonio
Опубликовано 2011

Preclinical evaluation of dasatinib alone and in combination with cabozantinib for the treatment of diffuse intrinsic pontine glioma

по Truffaux, Nathalène, Philippe, Cathy, Paulsson, Janna, Andreiuolo, Felipe, Guerrini-Rousseau, Léa, Cornilleau, Gaétan, Le Dret, Ludivine, Richon, Catherine, Lacroix, Ludovic, Puget, Stéphanie, Geoerger, Birgit, Vassal, Gilles, Östman, Arne, Grill, Jacques
Опубликовано в: Neuro Oncol (2015)

Bone Sarcomas: From Biology to Targeted Therapies

по Gaspar, Nathalie, Di Giannatale, Angela, Geoerger, Birgit, Redini, Françoise, Corradini, Nadège, Enz-Werle, Natacha, Tirode, Franck, Marec-Berard, Perrine, Gentet, Jean-Claude, Laurence, Valérie, Piperno-Neumann, Sophie, Oberlin, Odile, Brugieres, Laurence
Опубликовано 2012

EPT-13 RAPIRI I – PHASE I STUDY OF DAILY ORAL RAPAMYCIN AND INTRAVENOUS IRINOTECAN IN CHILDREN WITH A RECURRENT/REFRACTORY MALIGNANT SOLID TUMOR: GOOD TOLERANCE AND PROMISING RESUL...

по Jannier, Sarah, Kemmel, Veronique, Koob, Meriam, Farace, Françoise, Pencreach, Erwan, Geoerger, Birgit, Aerts, Isabelle, Faure-Conter, Cecile, Leblond, Pierre, Andre, Nicolas, Perel, Yves, Corradini, Nadège, Bertozzi, Anne Isabelle, Entz-Werlé, Natacha
Опубликовано в: Neuro Oncol (2016)

A phase 1 study of oral ridaforolimus in pediatric patients with advanced solid tumors

по Pearson, Andrew D.J., Federico, Sara M., Aerts, Isabelle, Hargrave, Darren R., DuBois, Steven G., Iannone, Robert, Geschwindt, Ryan D., Wang, Ruixue, Haluska, Frank G., Trippett, Tanya M., Geoerger, Birgit
Опубликовано в: Oncotarget (2016)

Transient stabilization, rather than inhibition of MYC amplifies extrinsic apoptosis and therapeutic responses in refractory B-cell lymphoma

по Harrington, Colleen T., Sotillo, Elena, Robert, Aude, Hayer, Katharina E., Bogusz, Agata M., Psathas, James, Yu, Duonan, Taylor, Deanne, Dang, Chi V., Klein, Peter, Hogarty, Michael D., Geoerger, Birgit, El-Deiry, Wafik S., Wiels, Joëlle, Thomas-Tikhonenko, Andrei
Опубликовано в: Leukemia (2019)

LGG-49. SAFETY AND EFFICACY OF TRAMETINIB (T) MONOTHERAPY AND DABRAFENIB + TRAMETINIB (D+T) COMBINATION THERAPY IN PEDIATRIC PATIENTS WITH BRAF V600-MUTANT LOW-GRADE GLIOMA (LGG)

по Bouffet, Eric, Whitlock, James A, Moertel, Christopher, Geoerger, Birgit, Aerts, Isabelle, Hargrave, Darren, Cohen, Kenneth J, Kilburn, Lindsay B, Upadhyaya, Santhosh A, Wetmore, Cynthia, Wright, Karen D, Choi, Jeea, Gasal, Eduard, Russo, Mark W, Fox, Elizabeth
Опубликовано в: Neuro Oncol (2020)