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PDCT-02. EVALUATION OF DEPATUXIZUMAB MAFODOTIN (ABT-414) IN CHILDREN WITH HIGH GRADE GLIOMA (HGG) AND DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG)
BACKGROUND: Pediatric HGGs (WHO grade III and IV gliomas) and DIPGs have no adequate therapy and are almost universally fatal. Depatuxizumab mafodotin (depatux-m), formerly called ABT-414, is an antibody-drug conjugate, comprised of an anti-EGFR antibody linked to a microtubule cytotoxin, monomethyl...
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| 發表在: | Neuro Oncol |
|---|---|
| Main Authors: | , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Oxford University Press
2017
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5693130/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.746 |
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