PDCT-02. EVALUATION OF DEPATUXIZUMAB MAFODOTIN (ABT-414) IN CHILDREN WITH HIGH GRADE GLIOMA (HGG) AND DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG)

BACKGROUND: Pediatric HGGs (WHO grade III and IV gliomas) and DIPGs have no adequate therapy and are almost universally fatal. Depatuxizumab mafodotin (depatux-m), formerly called ABT-414, is an antibody-drug conjugate, comprised of an anti-EGFR antibody linked to a microtubule cytotoxin, monomethyl...

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Publicado en:Neuro Oncol
Main Authors: van den Bent, Martin, Geoerger, Birgit, Golfinopoulos, Vassilis, Ansell, Peter J, Bain, Earle, Looman, Jim, Xiong, Hao, Fischer, JuDee, Holen, Kyle D, Hargrave, Darren
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5693130/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.746
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