PATH-29. MOLECULAR DETERMINANTS ASSOCIATED WITH RESPONSE AND RESISTANCE TO DEPATUXIZUMAB MAFODOTIN (ABT-414) IN PATIENTS WITH RECURRENT GLIOBLASTOMA

BACKGROUND: Depatuxizumab mafodotin (depatux-m, formerly ABT-414), is an EGFR-targeted antibody conjugated to the antimicrotubule agent monomethylauristatin F (MMAF). In an ongoing Phase I study, response in recurrent glioblastoma (rGBM) correlated with EGFR amplification in pre-treatment, archival...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Neuro Oncol
Egile Nagusiak: Lassman, Andrew, Roberts-Rapp, Lisa, He, Lei, Lu, Xin, van den Bent, Martin, Papadopoulos, Kyriakos, Merrell, Ryan, Kumthekar, Priya, Reardon, David, Gomez, Erica, Fischer, JuDee, Jiang, Fang, Zha, Zheng, Bhathena, Anahita, Holen, Kyle, Ansell, Peter, Gan, Hui K, Scott, Andrew
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2017
Gaiak:
Abstracts
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692486/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.719
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