ACTR-13. EPIDERMAL GROWTH FACTOR RECEPTOR (EGFR) AMPLIFICATION RATES OBSERVED IN SCREENING PATIENTS FOR RANDOMIZED CLINICAL TRIALS IN GLIOBLASTOMA

Por van den Bent, Martin, Roberts-Rapp, Lisa A, Ansell, Peter J, Lee, James, Looman, Jim, Bain, Earle, Ocampo, Christopher, Holen, Kyle D, Gomez, Erica J, Lassman, Andrew B
Publicado no Neuro Oncol (2017)

ACTR-68. CONCORDANCE OF EGFR AND MGMT ANALYSES BETWEEN LOCAL AND CENTRAL LABORATORIES: IMPLICATIONS FOR CLINICAL TRIAL DESIGN AND PRECISION MEDICINE FOR DEPATUXIZUMAB-MAFODOTIN (AB...

Por Lassman, Andrew, Dimino, Cara, Mansukhani, Mahesh, Murty, Vundavalli, Ansell, Peter J, Bain, Earle, Holen, Kyle D, Roberts-Rapp, Lisa A, Lee, James, Curran, Walter, Mehta, Minesh P, Canoll, Peter
Publicado no Neuro Oncol (2017)

Phase 1 Dose Escalation Trial of Ilorasertib, a Dual Aurora/VEGF Receptor Kinase Inhibitor, in Patients With Hematologic Malignancies

Por Garcia-Manero, Guillermo, Tibes, Raoul, Kadia, Tapan, Kantarjian, Hagop, Arellano, Martha, Knight, Emily A., Xiong, Hao, Qin, Qin, Munasinghe, Wijith, Roberts-Rapp, Lisa, Ansell, Peter, Albert, Daniel H., Oliver, Brian, McKee, Mark D., Ricker, Justin L., Khoury, Hanna Jean
Publicado no Invest New Drugs (2015)

PATH-29. MOLECULAR DETERMINANTS ASSOCIATED WITH RESPONSE AND RESISTANCE TO DEPATUXIZUMAB MAFODOTIN (ABT-414) IN PATIENTS WITH RECURRENT GLIOBLASTOMA

Por Lassman, Andrew, Roberts-Rapp, Lisa, He, Lei, Lu, Xin, van den Bent, Martin, Papadopoulos, Kyriakos, Merrell, Ryan, Kumthekar, Priya, Reardon, David, Gomez, Erica, Fischer, JuDee, Jiang, Fang, Zha, Zheng, Bhathena, Anahita, Holen, Kyle, Ansell, Peter, Gan, Hui K, Scott, Andrew
Publicado no Neuro Oncol (2017)

ET-19 A PHASE 1 STUDY EVALUATING ABT-414 WITH TEMOZOLOMIDE (TMZ) OR CONCURRENT RADIOTHERAPY (RT) AND TMZ IN GLIOBLASTOMA (GBM)

Por Gan, Hui K., Fichtel, Lisa, Lassman, Andrew B., Merrell, Ryan, van den Bent, Martin, Kumthekar, Priya, Scott, Andrew M., Pedersen, Michelle, Gomez, Erica, Fischer, JuDee, Ames, William, Xiong, Hao, Dudley, Matt, Munasinghe, Wijith, Roberts-Rapp, Lisa, Ansell, Peter, Holen, Kyle, Reardon, David A.
Publicado em 2014

ATNT-01 ABT-414 MONO- OR COMBINATION THERAPY WITH TEMOZOLOMIDE (TMZ) RECHALLENGE IN PATIENTS WITH RECURRENT GLIOBLASTOMA (GBM) AND AMPLIFIED EPIDERMAL GROWTH FACTOR RECEPTOR (EGFR)...

Por Gan, Hui K., Kumthekar, Priya, Lassman, Andrew B., Merrell, Ryan, van den Bent, Martin, Papadopoulos, Kyriakos P., Scott, Andrew M., Gomez, Erica, Fischer, JuDee, Mandich, Helen, Xiong, Hao, Lee, Ho-Jin, Munasinghe, Wijith, Roberts-Rapp, Lisa, Ansell, Peter, Holen, Kyle, Lai, Rose, Reardon, David A.
Publicado no Neuro Oncol (2015)

ATNT-02 DETERMINANTS OF RESPONSES AND RESISTANCE TO ABT-414: RESULTS OF NEXT-GENERATION SEQUENCING

Por Scott, Andrew M., Roberts-Rapp, Lisa, Gan, Hui K., Lu, Xin, Lassman, Andrew B., van den Bent, Martin, Papadopoulos, Kyriakos P., Merrell, Ryan, Kumthekar, Priya, Reardon, David A., Sokolova, Irina, Song, Minghao, Kular, Rupinder, Gomez, Erica, Fischer, JuDee, Bhathena, Anahita, Holen, Kyle, Lai, Rose, Ansell, Peter
Publicado no Neuro Oncol (2015)

Efficacy and safety results of ABT-414 in combination with radiation and temozolomide in newly diagnosed glioblastoma

Por Reardon, David A., Lassman, Andrew B., van den Bent, Martin, Kumthekar, Priya, Merrell, Ryan, Scott, Andrew M., Fichtel, Lisa, Sulman, Erik P., Gomez, Erica, Fischer, JuDee, Lee, Ho-Jin, Munasinghe, Wijith, Xiong, Hao, Mandich, Helen, Roberts-Rapp, Lisa, Ansell, Peter, Holen, Kyle D., Gan, Hui K.
Publicado no Neuro Oncol (2017)

Comparison of Biomarker Assays for EGFR: Implications for Precision Medicine in Patients with Glioblastoma

Por Lassman, Andrew B., Roberts-Rapp, Lisa, Sokolova, Irina, Song, Minghao, Pestova, Ekaterina, Kular, Rupinder, Mullen, Carolyn, Zha, Zheng, Lu, Xin, Gomez, Erica, Bhathena, Anahita, Maag, David, Kumthekar, Priya, Gan, Hui K., Scott, Andrew M., Guseva, Maria, Holen, Kyle D., Ansell, Peter J., van den Bent, Martin J.
Publicado no Clin Cancer Res (2019)

Safety, pharmacokinetics, and antitumor response of depatuxizumab mafodotin as monotherapy or in combination with temozolomide in patients with glioblastoma

Por Gan, Hui K, Reardon, David A, Lassman, Andrew B, Merrell, Ryan, van den Bent, Martin, Butowski, Nicholas, Lwin, Zarnie, Wheeler, Helen, Fichtel, Lisa, Scott, Andrew M, Gomez, Erica J, Fischer, JuDee, Mandich, Helen, Xiong, Hao, Lee, Ho-Jin, Munasinghe, Wijith P, Roberts-Rapp, Lisa A, Ansell, Peter J, Holen, Kyle D, Kumthekar, Priya
Publicado no Neuro Oncol (2018)

Efficacy and safety results of depatuxizumab mafodotin (ABT‐414) in patients with advanced solid tumors likely to overexpress epidermal growth factor receptor

Por Goss, Glenwood D., Vokes, Everett E., Gordon, Michael S., Gandhi, Leena, Papadopoulos, Kyriakos P., Rasco, Drew W., Fischer, JuDee S., Chu, Katharine L., Ames, William W., Mittapalli, Rajendar K., Lee, Ho‐Jin, Zeng, Jiewei, Roberts‐Rapp, Lisa A., Loberg, Lise I., Ansell, Peter J., Reilly, Edward B., Ocampo, Christopher J., Holen, Kyle D., Tolcher, Anthony W.
Publicado no Cancer (2018)

Epidermal Growth Factor Receptor (EGFR) Amplification Rates Observed in Screening Patients for Randomized Trials in Glioblastoma

Por Lassman, Andrew B., Aldape, Kenneth D., Ansell, Peter J., Bain, Earle, Curran, Walter J., Eoli, Marica, French, Pim J., Kinoshita, Manabu, Looman, Jim, Mehta, Minesh, Muragaki, Yoshihiro, Narita, Yoshitaka, Ocampo, Christopher, Roberts-Rapp, Lisa, Song, Minghao, Vogelbaum, Michael A., Walenkamp, Annemiek M.E., Wang, Tony J. C., Zhang, Peixin, van den Bent, Martin J.
Publicado no J Neurooncol (2019)

Efficacy of depatuxizumab mafodotin (ABT-414) monotherapy in patients with EGFR-amplified, recurrent glioblastoma: results from a multi-center, international study

Por van den Bent, Martin, Gan, Hui K., Lassman, Andrew B., Kumthekar, Priya, Merrell, Ryan, Butowski, Nicholas, Lwin, Zarnie, Mikkelsen, Tom, Nabors, Louis B., Papadopoulos, Kyriakos P., Penas-Prado, Marta, Simes, John, Wheeler, Helen, Walbert, Tobias, Scott, Andrew M., Gomez, Erica, Lee, Ho-Jin, Roberts-Rapp, Lisa, Xiong, Hao, Bain, Earle, Ansell, Peter J., Holen, Kyle D., Maag, David, Reardon, David A.
Publicado no Cancer Chemother Pharmacol (2017)

Safety and efficacy of depatuxizumab mafodotin + temozolomide in patients with EGFR-amplified, recurrent glioblastoma: results from an international phase I multicenter trial

Por Lassman, Andrew B, van den Bent, Martin J, Gan, Hui K, Reardon, David A, Kumthekar, Priya, Butowski, Nicholas, Lwin, Zarnie, Mikkelsen, Tom, Nabors, Louis B, Papadopoulos, Kyriakos P, Penas-Prado, Marta, Simes, John, Wheeler, Helen, Walbert, Tobias, Scott, Andrew M, Gomez, Erica, Lee, Ho-Jin, Roberts-Rapp, Lisa, Xiong, Hao, Ansell, Peter J, Bain, Earle, Holen, Kyle D, Maag, David, Merrell, Ryan
Publicado no Neuro Oncol (2019)