ACTR-13. EPIDERMAL GROWTH FACTOR RECEPTOR (EGFR) AMPLIFICATION RATES OBSERVED IN SCREENING PATIENTS FOR RANDOMIZED CLINICAL TRIALS IN GLIOBLASTOMA

af van den Bent, Martin, Roberts-Rapp, Lisa A, Ansell, Peter J, Lee, James, Looman, Jim, Bain, Earle, Ocampo, Christopher, Holen, Kyle D, Gomez, Erica J, Lassman, Andrew B
Udgivet i Neuro Oncol (2017)

ACTR-68. CONCORDANCE OF EGFR AND MGMT ANALYSES BETWEEN LOCAL AND CENTRAL LABORATORIES: IMPLICATIONS FOR CLINICAL TRIAL DESIGN AND PRECISION MEDICINE FOR DEPATUXIZUMAB-MAFODOTIN (AB...

af Lassman, Andrew, Dimino, Cara, Mansukhani, Mahesh, Murty, Vundavalli, Ansell, Peter J, Bain, Earle, Holen, Kyle D, Roberts-Rapp, Lisa A, Lee, James, Curran, Walter, Mehta, Minesh P, Canoll, Peter
Udgivet i Neuro Oncol (2017)

Phase 1 Dose Escalation Trial of Ilorasertib, a Dual Aurora/VEGF Receptor Kinase Inhibitor, in Patients With Hematologic Malignancies

af Garcia-Manero, Guillermo, Tibes, Raoul, Kadia, Tapan, Kantarjian, Hagop, Arellano, Martha, Knight, Emily A., Xiong, Hao, Qin, Qin, Munasinghe, Wijith, Roberts-Rapp, Lisa, Ansell, Peter, Albert, Daniel H., Oliver, Brian, McKee, Mark D., Ricker, Justin L., Khoury, Hanna Jean
Udgivet i Invest New Drugs (2015)

PATH-29. MOLECULAR DETERMINANTS ASSOCIATED WITH RESPONSE AND RESISTANCE TO DEPATUXIZUMAB MAFODOTIN (ABT-414) IN PATIENTS WITH RECURRENT GLIOBLASTOMA

af Lassman, Andrew, Roberts-Rapp, Lisa, He, Lei, Lu, Xin, van den Bent, Martin, Papadopoulos, Kyriakos, Merrell, Ryan, Kumthekar, Priya, Reardon, David, Gomez, Erica, Fischer, JuDee, Jiang, Fang, Zha, Zheng, Bhathena, Anahita, Holen, Kyle, Ansell, Peter, Gan, Hui K, Scott, Andrew
Udgivet i Neuro Oncol (2017)

ET-19 A PHASE 1 STUDY EVALUATING ABT-414 WITH TEMOZOLOMIDE (TMZ) OR CONCURRENT RADIOTHERAPY (RT) AND TMZ IN GLIOBLASTOMA (GBM)

af Gan, Hui K., Fichtel, Lisa, Lassman, Andrew B., Merrell, Ryan, van den Bent, Martin, Kumthekar, Priya, Scott, Andrew M., Pedersen, Michelle, Gomez, Erica, Fischer, JuDee, Ames, William, Xiong, Hao, Dudley, Matt, Munasinghe, Wijith, Roberts-Rapp, Lisa, Ansell, Peter, Holen, Kyle, Reardon, David A.
Udgivet 2014

ATNT-01 ABT-414 MONO- OR COMBINATION THERAPY WITH TEMOZOLOMIDE (TMZ) RECHALLENGE IN PATIENTS WITH RECURRENT GLIOBLASTOMA (GBM) AND AMPLIFIED EPIDERMAL GROWTH FACTOR RECEPTOR (EGFR)...

af Gan, Hui K., Kumthekar, Priya, Lassman, Andrew B., Merrell, Ryan, van den Bent, Martin, Papadopoulos, Kyriakos P., Scott, Andrew M., Gomez, Erica, Fischer, JuDee, Mandich, Helen, Xiong, Hao, Lee, Ho-Jin, Munasinghe, Wijith, Roberts-Rapp, Lisa, Ansell, Peter, Holen, Kyle, Lai, Rose, Reardon, David A.
Udgivet i Neuro Oncol (2015)

ATNT-02 DETERMINANTS OF RESPONSES AND RESISTANCE TO ABT-414: RESULTS OF NEXT-GENERATION SEQUENCING

af Scott, Andrew M., Roberts-Rapp, Lisa, Gan, Hui K., Lu, Xin, Lassman, Andrew B., van den Bent, Martin, Papadopoulos, Kyriakos P., Merrell, Ryan, Kumthekar, Priya, Reardon, David A., Sokolova, Irina, Song, Minghao, Kular, Rupinder, Gomez, Erica, Fischer, JuDee, Bhathena, Anahita, Holen, Kyle, Lai, Rose, Ansell, Peter
Udgivet i Neuro Oncol (2015)

Efficacy and safety results of ABT-414 in combination with radiation and temozolomide in newly diagnosed glioblastoma

af Reardon, David A., Lassman, Andrew B., van den Bent, Martin, Kumthekar, Priya, Merrell, Ryan, Scott, Andrew M., Fichtel, Lisa, Sulman, Erik P., Gomez, Erica, Fischer, JuDee, Lee, Ho-Jin, Munasinghe, Wijith, Xiong, Hao, Mandich, Helen, Roberts-Rapp, Lisa, Ansell, Peter, Holen, Kyle D., Gan, Hui K.
Udgivet i Neuro Oncol (2017)

Comparison of Biomarker Assays for EGFR: Implications for Precision Medicine in Patients with Glioblastoma

af Lassman, Andrew B., Roberts-Rapp, Lisa, Sokolova, Irina, Song, Minghao, Pestova, Ekaterina, Kular, Rupinder, Mullen, Carolyn, Zha, Zheng, Lu, Xin, Gomez, Erica, Bhathena, Anahita, Maag, David, Kumthekar, Priya, Gan, Hui K., Scott, Andrew M., Guseva, Maria, Holen, Kyle D., Ansell, Peter J., van den Bent, Martin J.
Udgivet i Clin Cancer Res (2019)

Safety, pharmacokinetics, and antitumor response of depatuxizumab mafodotin as monotherapy or in combination with temozolomide in patients with glioblastoma

af Gan, Hui K, Reardon, David A, Lassman, Andrew B, Merrell, Ryan, van den Bent, Martin, Butowski, Nicholas, Lwin, Zarnie, Wheeler, Helen, Fichtel, Lisa, Scott, Andrew M, Gomez, Erica J, Fischer, JuDee, Mandich, Helen, Xiong, Hao, Lee, Ho-Jin, Munasinghe, Wijith P, Roberts-Rapp, Lisa A, Ansell, Peter J, Holen, Kyle D, Kumthekar, Priya
Udgivet i Neuro Oncol (2018)

Efficacy and safety results of depatuxizumab mafodotin (ABT‐414) in patients with advanced solid tumors likely to overexpress epidermal growth factor receptor

af Goss, Glenwood D., Vokes, Everett E., Gordon, Michael S., Gandhi, Leena, Papadopoulos, Kyriakos P., Rasco, Drew W., Fischer, JuDee S., Chu, Katharine L., Ames, William W., Mittapalli, Rajendar K., Lee, Ho‐Jin, Zeng, Jiewei, Roberts‐Rapp, Lisa A., Loberg, Lise I., Ansell, Peter J., Reilly, Edward B., Ocampo, Christopher J., Holen, Kyle D., Tolcher, Anthony W.
Udgivet i Cancer (2018)

Epidermal Growth Factor Receptor (EGFR) Amplification Rates Observed in Screening Patients for Randomized Trials in Glioblastoma

af Lassman, Andrew B., Aldape, Kenneth D., Ansell, Peter J., Bain, Earle, Curran, Walter J., Eoli, Marica, French, Pim J., Kinoshita, Manabu, Looman, Jim, Mehta, Minesh, Muragaki, Yoshihiro, Narita, Yoshitaka, Ocampo, Christopher, Roberts-Rapp, Lisa, Song, Minghao, Vogelbaum, Michael A., Walenkamp, Annemiek M.E., Wang, Tony J. C., Zhang, Peixin, van den Bent, Martin J.
Udgivet i J Neurooncol (2019)

Efficacy of depatuxizumab mafodotin (ABT-414) monotherapy in patients with EGFR-amplified, recurrent glioblastoma: results from a multi-center, international study

af van den Bent, Martin, Gan, Hui K., Lassman, Andrew B., Kumthekar, Priya, Merrell, Ryan, Butowski, Nicholas, Lwin, Zarnie, Mikkelsen, Tom, Nabors, Louis B., Papadopoulos, Kyriakos P., Penas-Prado, Marta, Simes, John, Wheeler, Helen, Walbert, Tobias, Scott, Andrew M., Gomez, Erica, Lee, Ho-Jin, Roberts-Rapp, Lisa, Xiong, Hao, Bain, Earle, Ansell, Peter J., Holen, Kyle D., Maag, David, Reardon, David A.
Udgivet i Cancer Chemother Pharmacol (2017)

Safety and efficacy of depatuxizumab mafodotin + temozolomide in patients with EGFR-amplified, recurrent glioblastoma: results from an international phase I multicenter trial

af Lassman, Andrew B, van den Bent, Martin J, Gan, Hui K, Reardon, David A, Kumthekar, Priya, Butowski, Nicholas, Lwin, Zarnie, Mikkelsen, Tom, Nabors, Louis B, Papadopoulos, Kyriakos P, Penas-Prado, Marta, Simes, John, Wheeler, Helen, Walbert, Tobias, Scott, Andrew M, Gomez, Erica, Lee, Ho-Jin, Roberts-Rapp, Lisa, Xiong, Hao, Ansell, Peter J, Bain, Earle, Holen, Kyle D, Maag, David, Merrell, Ryan
Udgivet i Neuro Oncol (2019)