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Innovations for phase I dose-finding designs in pediatric oncology clinical trials
Phase I oncology clinical trials are designed to identify the optimal dose that will be recommended for phase II trials. In pediatric oncology, the conduct of those trials raise specific challenges, as the disease is rare with limited therapeutic options. In addition, the tolerance profile is known...
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| Publicado no: | Contemp Clin Trials |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4818190/ https://ncbi.nlm.nih.gov/pubmed/26825023 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cct.2016.01.009 |
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