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A comparative study of adaptive dose-finding designs for phase I oncology trials of combination therapies
Little is known about the relative performance of competing model-based dose-finding methods for combination phase I trials. In this study, we focused on five model-based dose-finding methods that have been recently developed. We compared the recommendation rates for true maximum-tolerated dose comb...
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| 發表在: | Stat Med |
|---|---|
| Main Authors: | , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2015
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4806394/ https://ncbi.nlm.nih.gov/pubmed/25974405 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.6533 |
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