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Seamless Phase I/II Adaptive Design For Oncology Trials of Molecularly Targeted Agents
In dose-finding trials of chemotherapeutic agents, the goal of identifying the maximum tolerated dose is usually determined by considering information on toxicity only, with the assumption that the highest safe dose also provides the most promising outlook for efficacy. Trials of molecularly targete...
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| 發表在: | J Biopharm Stat |
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| Main Authors: | , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2014
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4363077/ https://ncbi.nlm.nih.gov/pubmed/24904956 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10543406.2014.920873 |
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