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Phase I/II adaptive design for drug combination oncology trials
Existing statistical methodology on dose finding for combination chemotherapies has focused on toxicity considerations alone in finding a maximum tolerated dose combination to recommend for further testing of efficacy in a phase II setting. Recently, there has been increasing interest in integrating...
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| Publicado no: | Stat Med |
|---|---|
| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4258389/ https://ncbi.nlm.nih.gov/pubmed/24470329 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.6097 |
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