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Practical designs for phase I combination studies in oncology

Phase I trials evaluating the safety of multi-drug combinations are becoming more common in oncology. Despite the emergence of novel methodology in the area, it is rare that innovative approaches are used in practice. In this article, we review three methods for Phase I combination studies that are...

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Détails bibliographiques
Publié dans:J Biopharm Stat
Auteurs principaux: Wages, Nolan A., Ivanova, Anastasia, Marchenko, Olga
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4720553/
https://ncbi.nlm.nih.gov/pubmed/26379085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10543406.2015.1092029
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