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Practical considerations for the implementation of adaptive designs for oncology Phase I dose-finding trials
The traditional 3 + 3 design continues to be commonly used for Phase I dose-finding oncology trials, despite increasing criticisms and development of innovative methods. Unfortunately, it is a challenge to convince principal investigators to use novel designs. The goal of this paper is to persuade r...
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| Published in: | Future Drug Discov |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Newlands Press Ltd
2019
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6811732/ https://ncbi.nlm.nih.gov/pubmed/31656956 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fdd-2019-0021 |
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