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Practical considerations for the implementation of adaptive designs for oncology Phase I dose-finding trials

The traditional 3 + 3 design continues to be commonly used for Phase I dose-finding oncology trials, despite increasing criticisms and development of innovative methods. Unfortunately, it is a challenge to convince principal investigators to use novel designs. The goal of this paper is to persuade r...

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Bibliografiska uppgifter
I publikationen:Future Drug Discov
Huvudupphovsmän: Wei, Lai, Pan, Xueliang, Fernandez, Soledad
Materialtyp: Artigo
Språk:Inglês
Publicerad: Newlands Press Ltd 2019
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6811732/
https://ncbi.nlm.nih.gov/pubmed/31656956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fdd-2019-0021
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