A carregar...
Two-stage designs for Phase 2 dose-finding trials
We propose a Bayesian adaptive two-stage design for the efficient estimation of the maximum dose or the minimum effective dose in a dose-finding trial. The new design allocates subjects in stage two according to the posterior distribution of the target dose location. Simulations show that the propos...
Na minha lista:
| Main Authors: | , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4090751/ https://ncbi.nlm.nih.gov/pubmed/22865626 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.5365 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|