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Rapid enrollment design for finding the optimal dose in immunotherapy trials with ordered groups

In immunotherapy dose-finding trials, the optimal dose is usually defined based on both toxicity and response because the relationship between toxicity and response is different than that seen with cytotoxic antineoplastic therapies. In immunotherapy trials, toxicity and response often require a lon...

詳細記述

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書誌詳細
出版年:J Biopharm Stat
主要な著者: Xue, Xiaoqiang, Foster, Matthew C, Ivanova, Anastasia
フォーマット: Artigo
言語:Inglês
出版事項: 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6791120/
https://ncbi.nlm.nih.gov/pubmed/31251112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10543406.2019.1633654
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