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Rapid enrollment design for finding the optimal dose in immunotherapy trials with ordered groups
In immunotherapy dose-finding trials, the optimal dose is usually defined based on both toxicity and response because the relationship between toxicity and response is different than that seen with cytotoxic antineoplastic therapies. In immunotherapy trials, toxicity and response often require a lon...
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| Publicado no: | J Biopharm Stat |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6791120/ https://ncbi.nlm.nih.gov/pubmed/31251112 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10543406.2019.1633654 |
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