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Two-stage design for phase II oncology trials with relaxed futility stopping

Many oncology phase II trials are single arm studies designed to screen novel treatments based on efficacy outcome. Efficacy is often assessed as an ordinal variable based on a level of response of solid tumors with four categories: complete response, partial response, stable disease and progression...

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Detaylı Bibliyografya
Yayımlandı:Stat Interface
Asıl Yazarlar: Ivanova, Anastasia, Deal, Allison M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5969536/
https://ncbi.nlm.nih.gov/pubmed/29805727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4310/SII.2016.v9.n1.a9
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