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Two-stage design for phase II oncology trials with relaxed futility stopping
Many oncology phase II trials are single arm studies designed to screen novel treatments based on efficacy outcome. Efficacy is often assessed as an ordinal variable based on a level of response of solid tumors with four categories: complete response, partial response, stable disease and progression...
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| 發表在: | Stat Interface |
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| Main Authors: | , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2015
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5969536/ https://ncbi.nlm.nih.gov/pubmed/29805727 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4310/SII.2016.v9.n1.a9 |
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