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Two-stage design for phase II oncology trials with relaxed futility stopping
Many oncology phase II trials are single arm studies designed to screen novel treatments based on efficacy outcome. Efficacy is often assessed as an ordinal variable based on a level of response of solid tumors with four categories: complete response, partial response, stable disease and progression...
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| Publicado en: | Stat Interface |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5969536/ https://ncbi.nlm.nih.gov/pubmed/29805727 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4310/SII.2016.v9.n1.a9 |
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