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Enrollment and stopping rules for managing toxicity requiring long follow-up in Phase II oncology trials

Monitoring of toxicity is often conducted in Phase II trials in oncology to avoid an excessive number of toxicities if the wrong dose is chosen for Phase II. Existing stopping rules for toxicity use information from patients who have already completed follow-up. We describe a stopping rule that uses...

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Detaylı Bibliyografya
Yayımlandı:J Biopharm Stat
Asıl Yazarlar: Song, Guochen, Ivanova, Anastasia
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4689581/
https://ncbi.nlm.nih.gov/pubmed/26383917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10543406.2015.1086779
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