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Enrollment and stopping rules for managing toxicity requiring long follow-up in Phase II oncology trials
Monitoring of toxicity is often conducted in Phase II trials in oncology to avoid an excessive number of toxicities if the wrong dose is chosen for Phase II. Existing stopping rules for toxicity use information from patients who have already completed follow-up. We describe a stopping rule that uses...
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| Udgivet i: | J Biopharm Stat |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4689581/ https://ncbi.nlm.nih.gov/pubmed/26383917 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10543406.2015.1086779 |
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