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Histone deacetylase inhibitor panobinostat induces antitumor activity in epithelioid sarcoma and rhabdoid tumor by growth factor receptor modulation

BACKGROUND: Epithelioid sarcomas and rhabdoid tumors are rare, aggressive malignancies with poor prognosis. Both are characterized by INI1 alterations and deregulation of growth factor receptors albeit their interaction has not been elucidated. METHODS: In this study, we investigated the activity of...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:BMC Cancer
Main Authors: Harttrampf, Anne Catherine, da Costa, Maria Eugenia Marques, Renoult, Aline, Daudigeos-Dubus, Estelle, Geoerger, Birgit
פורמט: Artigo
שפה:Inglês
יצא לאור: BioMed Central 2021
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC8290558/
https://ncbi.nlm.nih.gov/pubmed/34281526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-021-08579-w
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