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Histone deacetylase inhibitors vorinostat and panobinostat induce G1 cell cycle arrest and apoptosis in multidrug resistant sarcoma cell lines

Synovial sarcoma and high grade chondrosarcoma are characterized by their lack of response to conventional cytotoxic chemotherapy, the tendency to develop lung metastases, and low survival rates. Research within the field prioritizes the development and expansion of new treatment options for dealing...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Bernhart, Eva, Stuendl, Nicole, Kaltenegger, Heike, Windpassinger, Christian, Donohue, Nicholas, Leithner, Andreas, Lohberger, Birgit
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5652778/
https://ncbi.nlm.nih.gov/pubmed/29100385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20460
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