Diacerein retards cell growth of chondrosarcoma cells at the G2/M cell cycle checkpoint via cyclin B1/CDK1 and CDK2 downregulation

BACKGROUND: Chondrosarcoma is characterized for its lack of response to conventional cytotoxic chemotherapy, propensity for developing lung metastases, and low rates of survival. Research within the field of development and expansion of new treatment options for unresectable or metastatic diseases i...

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Detaylı Bibliyografya
Yayımlandı:BMC Cancer
Asıl Yazarlar: Lohberger, Birgit, Leithner, Andreas, Stuendl, Nicole, Kaltenegger, Heike, Kullich, Werner, Steinecker-Frohnwieser, Bibiane
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2015
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4641423/
https://ncbi.nlm.nih.gov/pubmed/26555773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1915-4
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