Diacerein retards cell growth of chondrosarcoma cells at the G2/M cell cycle checkpoint via cyclin B1/CDK1 and CDK2 downregulation

BACKGROUND: Chondrosarcoma is characterized for its lack of response to conventional cytotoxic chemotherapy, propensity for developing lung metastases, and low rates of survival. Research within the field of development and expansion of new treatment options for unresectable or metastatic diseases i...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:BMC Cancer
Prif Awduron: Lohberger, Birgit, Leithner, Andreas, Stuendl, Nicole, Kaltenegger, Heike, Kullich, Werner, Steinecker-Frohnwieser, Bibiane
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2015
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4641423/
https://ncbi.nlm.nih.gov/pubmed/26555773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1915-4
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