Pharmacological treatment with diacerein combined with mechanical stimulation affects the expression of growth factors in human chondrocytes

BACKGROUND: Osteoarthritis (OA) as the main chronic joint disease arises from a disturbed balance between anabolic and catabolic processes leading to destructions of articular cartilage of the joints. While mechanical stress can be disastrous for the metabolism of chondrocytes, mechanical stimulatio...

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Vydáno v:Biochem Biophys Rep
Hlavní autoři: Steinecker-Frohnwieser, Bibiane, Kaltenegger, Heike, Weigl, Lukas, Mann, Anda, Kullich, Werner, Leithner, Andreas, Lohberger, Birgit
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2017
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5614688/
https://ncbi.nlm.nih.gov/pubmed/28955780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrep.2017.06.006
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