The Proteasome Inhibitor Bortezomib Affects Chondrosarcoma Cells via the Mitochondria-Caspase Dependent Pathway and Enhances Death Receptor Expression and Autophagy

High grade chondrosarcoma is characterized by its lack of response to conventional cytotoxic chemotherapy, the tendency to develop lung metastases, and low survival rates. Research within the field prioritizes the development and expansion of new treatment options for dealing with unresectable or me...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS One
Prif Awduron: Lohberger, Birgit, Steinecker-Frohnwieser, Bibiane, Stuendl, Nicole, Kaltenegger, Heike, Leithner, Andreas, Rinner, Beate
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2016
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5158315/
https://ncbi.nlm.nih.gov/pubmed/27978543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0168193
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