The Proteasome Inhibitor Bortezomib Affects Chondrosarcoma Cells via the Mitochondria-Caspase Dependent Pathway and Enhances Death Receptor Expression and Autophagy

High grade chondrosarcoma is characterized by its lack of response to conventional cytotoxic chemotherapy, the tendency to develop lung metastases, and low survival rates. Research within the field prioritizes the development and expansion of new treatment options for dealing with unresectable or me...

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Vydáno v:PLoS One
Hlavní autoři: Lohberger, Birgit, Steinecker-Frohnwieser, Bibiane, Stuendl, Nicole, Kaltenegger, Heike, Leithner, Andreas, Rinner, Beate
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2016
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5158315/
https://ncbi.nlm.nih.gov/pubmed/27978543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0168193
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