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The Proteasome Inhibitor Bortezomib Affects Chondrosarcoma Cells via the Mitochondria-Caspase Dependent Pathway and Enhances Death Receptor Expression and Autophagy

High grade chondrosarcoma is characterized by its lack of response to conventional cytotoxic chemotherapy, the tendency to develop lung metastases, and low survival rates. Research within the field prioritizes the development and expansion of new treatment options for dealing with unresectable or me...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Lohberger, Birgit, Steinecker-Frohnwieser, Bibiane, Stuendl, Nicole, Kaltenegger, Heike, Leithner, Andreas, Rinner, Beate
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5158315/
https://ncbi.nlm.nih.gov/pubmed/27978543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0168193
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