Phase II trial of temsirolimus in children with high-grade glioma, neuroblastoma and rhabdomyosarcoma()

PURPOSE: A phase II study of temsirolimus was conducted in children and adolescents with high-grade glioma, neuroblastoma or rhabdomyosarcoma. PATIENTS AND METHODS: Temsirolimus 75 mg/m(2) was administered once weekly until disease progression or intolerance. Using the Simon 2-stage design, further...

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主要な著者: Geoerger, Birgit, Kieran, Mark W., Grupp, Stephan, Perek, Danuta, Clancy, Jill, Krygowski, Mizue, Ananthakrishnan, Revathi, Boni, Joseph P., Berkenblit, Anna, Spunt, Sheri L.
フォーマット: Artigo
言語:Inglês
出版事項: 2011
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3539305/
https://ncbi.nlm.nih.gov/pubmed/22033322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejca.2011.09.021
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