Discovery of New Fusion Transcripts in a Cohort of Pediatric Solid Cancers at Relapse and Relevance for Personalized Medicine

We hypothetized that pediatric cancers would more likely harbor fusion transcripts. To dissect the complexity of the fusions landscape in recurrent solid pediatric cancers, we conducted a study on 48 patients with different relapsing or resistant malignancies. By analyzing RNA sequencing data with a...

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Detalhes bibliográficos
Publicado no:Mol Ther
Main Authors: Dupain, Célia, Harttrampf, Anne C., Boursin, Yannick, Lebeurrier, Manuel, Rondof, Windy, Robert-Siegwald, Guillaume, Khoueiry, Pierre, Geoerger, Birgit, Massaad-Massade, Liliane
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2019
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6319200/
https://ncbi.nlm.nih.gov/pubmed/30509566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2018.10.022
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