Innovations for phase I dose-finding designs in pediatric oncology clinical trials

par Doussau, Adelaide, Geoerger, Birgit, Jiménez, Irene, Paoletti, Xavier
Publié dans Contemp Clin Trials (2016)

Precision medicine in pediatric oncology

par Forrest, Suzanne J., Geoerger, Birgit, Janeway, Katherine A.
Publié dans Curr Opin Pediatr (2018)

Relevance of Fusion Genes in Pediatric Cancers: Toward Precision Medicine

par Dupain, Célia, Harttrampf, Anne Catherine, Urbinati, Giorgia, Geoerger, Birgit, Massaad-Massade, Liliane
Publié dans Mol Ther Nucleic Acids (2017)

Histone deacetylase inhibitor panobinostat induces antitumor activity in epithelioid sarcoma and rhabdoid tumor by growth factor receptor modulation

par Harttrampf, Anne Catherine, da Costa, Maria Eugenia Marques, Renoult, Aline, Daudigeos-Dubus, Estelle, Geoerger, Birgit
Publié dans BMC Cancer (2021)

Discovery of New Fusion Transcripts in a Cohort of Pediatric Solid Cancers at Relapse and Relevance for Personalized Medicine

par Dupain, Célia, Harttrampf, Anne C., Boursin, Yannick, Lebeurrier, Manuel, Rondof, Windy, Robert-Siegwald, Guillaume, Khoueiry, Pierre, Geoerger, Birgit, Massaad-Massade, Liliane
Publié dans Mol Ther (2019)

Phase II trial of temsirolimus in children with high-grade glioma, neuroblastoma and rhabdomyosarcoma()

par Geoerger, Birgit, Kieran, Mark W., Grupp, Stephan, Perek, Danuta, Clancy, Jill, Krygowski, Mizue, Ananthakrishnan, Revathi, Boni, Joseph P., Berkenblit, Anna, Spunt, Sheri L.
Publié 2011

HG-44 EVALUATION OF ABT-414 IN CHILDREN WITH HIGH GRADE GLIOMA (HGG) AND DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG)

par van den Bent, Martin, Geoerger, Birgit, Golfinopoulos, Vassilis, Ansell, Peter, Bain, Earle, Looman, Jim, Xiong, Hao, Fischer, JuDee, Holen, Kyle, Hargrave, Darren
Publié dans Neuro Oncol (2016)

A Perspective on Polo-Like Kinase-1 Inhibition for the Treatment of Rhabdomyosarcomas

par Gatz, Susanne A., Aladowicz, Ewa, Casanova, Michela, Chisholm, Julia C., Kearns, Pamela R., Fulda, Simone, Geoerger, Birgit, Schäfer, Beat W., Shipley, Janet M.
Publié dans Front Oncol (2019)

LGG-46. TRAMETINIB THERAPY IN PEDIATRIC PATIENTS WITH LOW-GRADE GLIOMAS (LGG) WITH BRAF GENE FUSION; A DISEASE-SPECIFIC COHORT IN THE FIRST PEDIATRIC TESTING OF TRAMETINIB

par Bouffet, Eric, Kieran, Mark, Hargrave, Darren, Roberts, Stephen, Aerts, Isabelle, Broniscer, Alberto, Geoerger, Birgit, Dasgupta, Kohinoor, Tseng, Lillian, Russo, Mark, Mookerjee, Bijoyesh, Moertel, Christopher
Publié dans Neuro Oncol (2018)

PDCT-02. EVALUATION OF DEPATUXIZUMAB MAFODOTIN (ABT-414) IN CHILDREN WITH HIGH GRADE GLIOMA (HGG) AND DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG)

par van den Bent, Martin, Geoerger, Birgit, Golfinopoulos, Vassilis, Ansell, Peter J, Bain, Earle, Looman, Jim, Xiong, Hao, Fischer, JuDee, Holen, Kyle D, Hargrave, Darren
Publié dans Neuro Oncol (2017)

Establishment and characterization of in vivo orthotopic bioluminescent xenograft models from human osteosarcoma cell lines in Swiss nude and NSG mice

par Marques da Costa, Maria Eugenia, Daudigeos‐Dubus, Estelle, Gomez‐Brouchet, Anne, Bawa, Olivia, Rouffiac, Valerie, Serra, Massimo, Scotlandi, Katia, Santos, Conceição, Geoerger, Birgit, Gaspar, Nathalie
Publié dans Cancer Med (2018)

In-Vitro and In-Vivo Establishment and Characterization of Bioluminescent Orthotopic Chemotherapy-Resistant Human Osteosarcoma Models in NSG Mice

par Marques da Costa, Maria Eugénia, Marchais, Antonin, Gomez-Brouchet, Anne, Job, Bastien, Assoun, Noémie, Daudigeos-Dubus, Estelle, Fromigué, Olivia, Santos, Conceição, Geoerger, Birgit, Gaspar, Nathalie
Publié dans Cancers (Basel) (2019)

Regorafenib: Antitumor Activity upon Mono and Combination Therapy in Preclinical Pediatric Malignancy Models

par Daudigeos-Dubus, Estelle, Le Dret, Ludivine, Lanvers-Kaminsky, Claudia, Bawa, Olivia, Opolon, Paule, Vievard, Albane, Villa, Irène, Pagès, Mélanie, Bosq, Jacques, Vassal, Gilles, Zopf, Dieter, Geoerger, Birgit
Publié dans PLoS One (2015)

Preliminary Efficacy of the Anti-Insulin–Like Growth Factor Type 1 Receptor Antibody Figitumumab in Patients With Refractory Ewing Sarcoma

par Juergens, Heribert, Daw, Najat C., Geoerger, Birgit, Ferrari, Stefano, Villarroel, Milena, Aerts, Isabelle, Whelan, Jeremy, Dirksen, Uta, Hixon, Mary L., Yin, Donghua, Wang, Tao, Green, Stephanie, Paccagnella, Luisa, Gualberto, Antonio
Publié 2011

Preclinical evaluation of dasatinib alone and in combination with cabozantinib for the treatment of diffuse intrinsic pontine glioma

par Truffaux, Nathalène, Philippe, Cathy, Paulsson, Janna, Andreiuolo, Felipe, Guerrini-Rousseau, Léa, Cornilleau, Gaétan, Le Dret, Ludivine, Richon, Catherine, Lacroix, Ludovic, Puget, Stéphanie, Geoerger, Birgit, Vassal, Gilles, Östman, Arne, Grill, Jacques
Publié dans Neuro Oncol (2015)

Bone Sarcomas: From Biology to Targeted Therapies

par Gaspar, Nathalie, Di Giannatale, Angela, Geoerger, Birgit, Redini, Françoise, Corradini, Nadège, Enz-Werle, Natacha, Tirode, Franck, Marec-Berard, Perrine, Gentet, Jean-Claude, Laurence, Valérie, Piperno-Neumann, Sophie, Oberlin, Odile, Brugieres, Laurence
Publié 2012

EPT-13 RAPIRI I – PHASE I STUDY OF DAILY ORAL RAPAMYCIN AND INTRAVENOUS IRINOTECAN IN CHILDREN WITH A RECURRENT/REFRACTORY MALIGNANT SOLID TUMOR: GOOD TOLERANCE AND PROMISING RESUL...

par Jannier, Sarah, Kemmel, Veronique, Koob, Meriam, Farace, Françoise, Pencreach, Erwan, Geoerger, Birgit, Aerts, Isabelle, Faure-Conter, Cecile, Leblond, Pierre, Andre, Nicolas, Perel, Yves, Corradini, Nadège, Bertozzi, Anne Isabelle, Entz-Werlé, Natacha
Publié dans Neuro Oncol (2016)

A phase 1 study of oral ridaforolimus in pediatric patients with advanced solid tumors

par Pearson, Andrew D.J., Federico, Sara M., Aerts, Isabelle, Hargrave, Darren R., DuBois, Steven G., Iannone, Robert, Geschwindt, Ryan D., Wang, Ruixue, Haluska, Frank G., Trippett, Tanya M., Geoerger, Birgit
Publié dans Oncotarget (2016)

Transient stabilization, rather than inhibition of MYC amplifies extrinsic apoptosis and therapeutic responses in refractory B-cell lymphoma

par Harrington, Colleen T., Sotillo, Elena, Robert, Aude, Hayer, Katharina E., Bogusz, Agata M., Psathas, James, Yu, Duonan, Taylor, Deanne, Dang, Chi V., Klein, Peter, Hogarty, Michael D., Geoerger, Birgit, El-Deiry, Wafik S., Wiels, Joëlle, Thomas-Tikhonenko, Andrei
Publié dans Leukemia (2019)

LGG-49. SAFETY AND EFFICACY OF TRAMETINIB (T) MONOTHERAPY AND DABRAFENIB + TRAMETINIB (D+T) COMBINATION THERAPY IN PEDIATRIC PATIENTS WITH BRAF V600-MUTANT LOW-GRADE GLIOMA (LGG)

par Bouffet, Eric, Whitlock, James A, Moertel, Christopher, Geoerger, Birgit, Aerts, Isabelle, Hargrave, Darren, Cohen, Kenneth J, Kilburn, Lindsay B, Upadhyaya, Santhosh A, Wetmore, Cynthia, Wright, Karen D, Choi, Jeea, Gasal, Eduard, Russo, Mark W, Fox, Elizabeth
Publié dans Neuro Oncol (2020)