Innovations for phase I dose-finding designs in pediatric oncology clinical trials

by Doussau, Adelaide, Geoerger, Birgit, Jiménez, Irene, Paoletti, Xavier
Published in Contemp Clin Trials (2016)

Precision medicine in pediatric oncology

by Forrest, Suzanne J., Geoerger, Birgit, Janeway, Katherine A.
Published in Curr Opin Pediatr (2018)

Relevance of Fusion Genes in Pediatric Cancers: Toward Precision Medicine

by Dupain, Célia, Harttrampf, Anne Catherine, Urbinati, Giorgia, Geoerger, Birgit, Massaad-Massade, Liliane
Published in Mol Ther Nucleic Acids (2017)

Histone deacetylase inhibitor panobinostat induces antitumor activity in epithelioid sarcoma and rhabdoid tumor by growth factor receptor modulation

by Harttrampf, Anne Catherine, da Costa, Maria Eugenia Marques, Renoult, Aline, Daudigeos-Dubus, Estelle, Geoerger, Birgit
Published in BMC Cancer (2021)

Discovery of New Fusion Transcripts in a Cohort of Pediatric Solid Cancers at Relapse and Relevance for Personalized Medicine

by Dupain, Célia, Harttrampf, Anne C., Boursin, Yannick, Lebeurrier, Manuel, Rondof, Windy, Robert-Siegwald, Guillaume, Khoueiry, Pierre, Geoerger, Birgit, Massaad-Massade, Liliane
Published in Mol Ther (2019)

Phase II trial of temsirolimus in children with high-grade glioma, neuroblastoma and rhabdomyosarcoma()

by Geoerger, Birgit, Kieran, Mark W., Grupp, Stephan, Perek, Danuta, Clancy, Jill, Krygowski, Mizue, Ananthakrishnan, Revathi, Boni, Joseph P., Berkenblit, Anna, Spunt, Sheri L.
Published 2011

HG-44 EVALUATION OF ABT-414 IN CHILDREN WITH HIGH GRADE GLIOMA (HGG) AND DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG)

by van den Bent, Martin, Geoerger, Birgit, Golfinopoulos, Vassilis, Ansell, Peter, Bain, Earle, Looman, Jim, Xiong, Hao, Fischer, JuDee, Holen, Kyle, Hargrave, Darren
Published in Neuro Oncol (2016)

A Perspective on Polo-Like Kinase-1 Inhibition for the Treatment of Rhabdomyosarcomas

by Gatz, Susanne A., Aladowicz, Ewa, Casanova, Michela, Chisholm, Julia C., Kearns, Pamela R., Fulda, Simone, Geoerger, Birgit, Schäfer, Beat W., Shipley, Janet M.
Published in Front Oncol (2019)

LGG-46. TRAMETINIB THERAPY IN PEDIATRIC PATIENTS WITH LOW-GRADE GLIOMAS (LGG) WITH BRAF GENE FUSION; A DISEASE-SPECIFIC COHORT IN THE FIRST PEDIATRIC TESTING OF TRAMETINIB

by Bouffet, Eric, Kieran, Mark, Hargrave, Darren, Roberts, Stephen, Aerts, Isabelle, Broniscer, Alberto, Geoerger, Birgit, Dasgupta, Kohinoor, Tseng, Lillian, Russo, Mark, Mookerjee, Bijoyesh, Moertel, Christopher
Published in Neuro Oncol (2018)

PDCT-02. EVALUATION OF DEPATUXIZUMAB MAFODOTIN (ABT-414) IN CHILDREN WITH HIGH GRADE GLIOMA (HGG) AND DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG)

by van den Bent, Martin, Geoerger, Birgit, Golfinopoulos, Vassilis, Ansell, Peter J, Bain, Earle, Looman, Jim, Xiong, Hao, Fischer, JuDee, Holen, Kyle D, Hargrave, Darren
Published in Neuro Oncol (2017)

Establishment and characterization of in vivo orthotopic bioluminescent xenograft models from human osteosarcoma cell lines in Swiss nude and NSG mice

by Marques da Costa, Maria Eugenia, Daudigeos‐Dubus, Estelle, Gomez‐Brouchet, Anne, Bawa, Olivia, Rouffiac, Valerie, Serra, Massimo, Scotlandi, Katia, Santos, Conceição, Geoerger, Birgit, Gaspar, Nathalie
Published in Cancer Med (2018)

In-Vitro and In-Vivo Establishment and Characterization of Bioluminescent Orthotopic Chemotherapy-Resistant Human Osteosarcoma Models in NSG Mice

by Marques da Costa, Maria Eugénia, Marchais, Antonin, Gomez-Brouchet, Anne, Job, Bastien, Assoun, Noémie, Daudigeos-Dubus, Estelle, Fromigué, Olivia, Santos, Conceição, Geoerger, Birgit, Gaspar, Nathalie
Published in Cancers (Basel) (2019)

Regorafenib: Antitumor Activity upon Mono and Combination Therapy in Preclinical Pediatric Malignancy Models

by Daudigeos-Dubus, Estelle, Le Dret, Ludivine, Lanvers-Kaminsky, Claudia, Bawa, Olivia, Opolon, Paule, Vievard, Albane, Villa, Irène, Pagès, Mélanie, Bosq, Jacques, Vassal, Gilles, Zopf, Dieter, Geoerger, Birgit
Published in PLoS One (2015)

Preliminary Efficacy of the Anti-Insulin–Like Growth Factor Type 1 Receptor Antibody Figitumumab in Patients With Refractory Ewing Sarcoma

by Juergens, Heribert, Daw, Najat C., Geoerger, Birgit, Ferrari, Stefano, Villarroel, Milena, Aerts, Isabelle, Whelan, Jeremy, Dirksen, Uta, Hixon, Mary L., Yin, Donghua, Wang, Tao, Green, Stephanie, Paccagnella, Luisa, Gualberto, Antonio
Published 2011

Preclinical evaluation of dasatinib alone and in combination with cabozantinib for the treatment of diffuse intrinsic pontine glioma

by Truffaux, Nathalène, Philippe, Cathy, Paulsson, Janna, Andreiuolo, Felipe, Guerrini-Rousseau, Léa, Cornilleau, Gaétan, Le Dret, Ludivine, Richon, Catherine, Lacroix, Ludovic, Puget, Stéphanie, Geoerger, Birgit, Vassal, Gilles, Östman, Arne, Grill, Jacques
Published in Neuro Oncol (2015)

Bone Sarcomas: From Biology to Targeted Therapies

by Gaspar, Nathalie, Di Giannatale, Angela, Geoerger, Birgit, Redini, Françoise, Corradini, Nadège, Enz-Werle, Natacha, Tirode, Franck, Marec-Berard, Perrine, Gentet, Jean-Claude, Laurence, Valérie, Piperno-Neumann, Sophie, Oberlin, Odile, Brugieres, Laurence
Published 2012

EPT-13 RAPIRI I – PHASE I STUDY OF DAILY ORAL RAPAMYCIN AND INTRAVENOUS IRINOTECAN IN CHILDREN WITH A RECURRENT/REFRACTORY MALIGNANT SOLID TUMOR: GOOD TOLERANCE AND PROMISING RESUL...

by Jannier, Sarah, Kemmel, Veronique, Koob, Meriam, Farace, Françoise, Pencreach, Erwan, Geoerger, Birgit, Aerts, Isabelle, Faure-Conter, Cecile, Leblond, Pierre, Andre, Nicolas, Perel, Yves, Corradini, Nadège, Bertozzi, Anne Isabelle, Entz-Werlé, Natacha
Published in Neuro Oncol (2016)

A phase 1 study of oral ridaforolimus in pediatric patients with advanced solid tumors

by Pearson, Andrew D.J., Federico, Sara M., Aerts, Isabelle, Hargrave, Darren R., DuBois, Steven G., Iannone, Robert, Geschwindt, Ryan D., Wang, Ruixue, Haluska, Frank G., Trippett, Tanya M., Geoerger, Birgit
Published in Oncotarget (2016)

Transient stabilization, rather than inhibition of MYC amplifies extrinsic apoptosis and therapeutic responses in refractory B-cell lymphoma

by Harrington, Colleen T., Sotillo, Elena, Robert, Aude, Hayer, Katharina E., Bogusz, Agata M., Psathas, James, Yu, Duonan, Taylor, Deanne, Dang, Chi V., Klein, Peter, Hogarty, Michael D., Geoerger, Birgit, El-Deiry, Wafik S., Wiels, Joëlle, Thomas-Tikhonenko, Andrei
Published in Leukemia (2019)

LGG-49. SAFETY AND EFFICACY OF TRAMETINIB (T) MONOTHERAPY AND DABRAFENIB + TRAMETINIB (D+T) COMBINATION THERAPY IN PEDIATRIC PATIENTS WITH BRAF V600-MUTANT LOW-GRADE GLIOMA (LGG)

by Bouffet, Eric, Whitlock, James A, Moertel, Christopher, Geoerger, Birgit, Aerts, Isabelle, Hargrave, Darren, Cohen, Kenneth J, Kilburn, Lindsay B, Upadhyaya, Santhosh A, Wetmore, Cynthia, Wright, Karen D, Choi, Jeea, Gasal, Eduard, Russo, Mark W, Fox, Elizabeth
Published in Neuro Oncol (2020)