Innovations for phase I dose-finding designs in pediatric oncology clinical trials

Autor Doussau, Adelaide, Geoerger, Birgit, Jiménez, Irene, Paoletti, Xavier
Vydáno v Contemp Clin Trials (2016)

Precision medicine in pediatric oncology

Autor Forrest, Suzanne J., Geoerger, Birgit, Janeway, Katherine A.
Vydáno v Curr Opin Pediatr (2018)

Relevance of Fusion Genes in Pediatric Cancers: Toward Precision Medicine

Autor Dupain, Célia, Harttrampf, Anne Catherine, Urbinati, Giorgia, Geoerger, Birgit, Massaad-Massade, Liliane
Vydáno v Mol Ther Nucleic Acids (2017)

Histone deacetylase inhibitor panobinostat induces antitumor activity in epithelioid sarcoma and rhabdoid tumor by growth factor receptor modulation

Autor Harttrampf, Anne Catherine, da Costa, Maria Eugenia Marques, Renoult, Aline, Daudigeos-Dubus, Estelle, Geoerger, Birgit
Vydáno v BMC Cancer (2021)

Discovery of New Fusion Transcripts in a Cohort of Pediatric Solid Cancers at Relapse and Relevance for Personalized Medicine

Autor Dupain, Célia, Harttrampf, Anne C., Boursin, Yannick, Lebeurrier, Manuel, Rondof, Windy, Robert-Siegwald, Guillaume, Khoueiry, Pierre, Geoerger, Birgit, Massaad-Massade, Liliane
Vydáno v Mol Ther (2019)

Phase II trial of temsirolimus in children with high-grade glioma, neuroblastoma and rhabdomyosarcoma()

Autor Geoerger, Birgit, Kieran, Mark W., Grupp, Stephan, Perek, Danuta, Clancy, Jill, Krygowski, Mizue, Ananthakrishnan, Revathi, Boni, Joseph P., Berkenblit, Anna, Spunt, Sheri L.
Vydáno 2011

HG-44 EVALUATION OF ABT-414 IN CHILDREN WITH HIGH GRADE GLIOMA (HGG) AND DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG)

Autor van den Bent, Martin, Geoerger, Birgit, Golfinopoulos, Vassilis, Ansell, Peter, Bain, Earle, Looman, Jim, Xiong, Hao, Fischer, JuDee, Holen, Kyle, Hargrave, Darren
Vydáno v Neuro Oncol (2016)

A Perspective on Polo-Like Kinase-1 Inhibition for the Treatment of Rhabdomyosarcomas

Autor Gatz, Susanne A., Aladowicz, Ewa, Casanova, Michela, Chisholm, Julia C., Kearns, Pamela R., Fulda, Simone, Geoerger, Birgit, Schäfer, Beat W., Shipley, Janet M.
Vydáno v Front Oncol (2019)

LGG-46. TRAMETINIB THERAPY IN PEDIATRIC PATIENTS WITH LOW-GRADE GLIOMAS (LGG) WITH BRAF GENE FUSION; A DISEASE-SPECIFIC COHORT IN THE FIRST PEDIATRIC TESTING OF TRAMETINIB

Autor Bouffet, Eric, Kieran, Mark, Hargrave, Darren, Roberts, Stephen, Aerts, Isabelle, Broniscer, Alberto, Geoerger, Birgit, Dasgupta, Kohinoor, Tseng, Lillian, Russo, Mark, Mookerjee, Bijoyesh, Moertel, Christopher
Vydáno v Neuro Oncol (2018)

PDCT-02. EVALUATION OF DEPATUXIZUMAB MAFODOTIN (ABT-414) IN CHILDREN WITH HIGH GRADE GLIOMA (HGG) AND DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG)

Autor van den Bent, Martin, Geoerger, Birgit, Golfinopoulos, Vassilis, Ansell, Peter J, Bain, Earle, Looman, Jim, Xiong, Hao, Fischer, JuDee, Holen, Kyle D, Hargrave, Darren
Vydáno v Neuro Oncol (2017)

Establishment and characterization of in vivo orthotopic bioluminescent xenograft models from human osteosarcoma cell lines in Swiss nude and NSG mice

Autor Marques da Costa, Maria Eugenia, Daudigeos‐Dubus, Estelle, Gomez‐Brouchet, Anne, Bawa, Olivia, Rouffiac, Valerie, Serra, Massimo, Scotlandi, Katia, Santos, Conceição, Geoerger, Birgit, Gaspar, Nathalie
Vydáno v Cancer Med (2018)

In-Vitro and In-Vivo Establishment and Characterization of Bioluminescent Orthotopic Chemotherapy-Resistant Human Osteosarcoma Models in NSG Mice

Autor Marques da Costa, Maria Eugénia, Marchais, Antonin, Gomez-Brouchet, Anne, Job, Bastien, Assoun, Noémie, Daudigeos-Dubus, Estelle, Fromigué, Olivia, Santos, Conceição, Geoerger, Birgit, Gaspar, Nathalie
Vydáno v Cancers (Basel) (2019)

Regorafenib: Antitumor Activity upon Mono and Combination Therapy in Preclinical Pediatric Malignancy Models

Autor Daudigeos-Dubus, Estelle, Le Dret, Ludivine, Lanvers-Kaminsky, Claudia, Bawa, Olivia, Opolon, Paule, Vievard, Albane, Villa, Irène, Pagès, Mélanie, Bosq, Jacques, Vassal, Gilles, Zopf, Dieter, Geoerger, Birgit
Vydáno v PLoS One (2015)

Preliminary Efficacy of the Anti-Insulin–Like Growth Factor Type 1 Receptor Antibody Figitumumab in Patients With Refractory Ewing Sarcoma

Autor Juergens, Heribert, Daw, Najat C., Geoerger, Birgit, Ferrari, Stefano, Villarroel, Milena, Aerts, Isabelle, Whelan, Jeremy, Dirksen, Uta, Hixon, Mary L., Yin, Donghua, Wang, Tao, Green, Stephanie, Paccagnella, Luisa, Gualberto, Antonio
Vydáno 2011

Preclinical evaluation of dasatinib alone and in combination with cabozantinib for the treatment of diffuse intrinsic pontine glioma

Autor Truffaux, Nathalène, Philippe, Cathy, Paulsson, Janna, Andreiuolo, Felipe, Guerrini-Rousseau, Léa, Cornilleau, Gaétan, Le Dret, Ludivine, Richon, Catherine, Lacroix, Ludovic, Puget, Stéphanie, Geoerger, Birgit, Vassal, Gilles, Östman, Arne, Grill, Jacques
Vydáno v Neuro Oncol (2015)

Bone Sarcomas: From Biology to Targeted Therapies

Autor Gaspar, Nathalie, Di Giannatale, Angela, Geoerger, Birgit, Redini, Françoise, Corradini, Nadège, Enz-Werle, Natacha, Tirode, Franck, Marec-Berard, Perrine, Gentet, Jean-Claude, Laurence, Valérie, Piperno-Neumann, Sophie, Oberlin, Odile, Brugieres, Laurence
Vydáno 2012

EPT-13 RAPIRI I – PHASE I STUDY OF DAILY ORAL RAPAMYCIN AND INTRAVENOUS IRINOTECAN IN CHILDREN WITH A RECURRENT/REFRACTORY MALIGNANT SOLID TUMOR: GOOD TOLERANCE AND PROMISING RESUL...

Autor Jannier, Sarah, Kemmel, Veronique, Koob, Meriam, Farace, Françoise, Pencreach, Erwan, Geoerger, Birgit, Aerts, Isabelle, Faure-Conter, Cecile, Leblond, Pierre, Andre, Nicolas, Perel, Yves, Corradini, Nadège, Bertozzi, Anne Isabelle, Entz-Werlé, Natacha
Vydáno v Neuro Oncol (2016)

A phase 1 study of oral ridaforolimus in pediatric patients with advanced solid tumors

Autor Pearson, Andrew D.J., Federico, Sara M., Aerts, Isabelle, Hargrave, Darren R., DuBois, Steven G., Iannone, Robert, Geschwindt, Ryan D., Wang, Ruixue, Haluska, Frank G., Trippett, Tanya M., Geoerger, Birgit
Vydáno v Oncotarget (2016)

Transient stabilization, rather than inhibition of MYC amplifies extrinsic apoptosis and therapeutic responses in refractory B-cell lymphoma

Autor Harrington, Colleen T., Sotillo, Elena, Robert, Aude, Hayer, Katharina E., Bogusz, Agata M., Psathas, James, Yu, Duonan, Taylor, Deanne, Dang, Chi V., Klein, Peter, Hogarty, Michael D., Geoerger, Birgit, El-Deiry, Wafik S., Wiels, Joëlle, Thomas-Tikhonenko, Andrei
Vydáno v Leukemia (2019)

LGG-49. SAFETY AND EFFICACY OF TRAMETINIB (T) MONOTHERAPY AND DABRAFENIB + TRAMETINIB (D+T) COMBINATION THERAPY IN PEDIATRIC PATIENTS WITH BRAF V600-MUTANT LOW-GRADE GLIOMA (LGG)

Autor Bouffet, Eric, Whitlock, James A, Moertel, Christopher, Geoerger, Birgit, Aerts, Isabelle, Hargrave, Darren, Cohen, Kenneth J, Kilburn, Lindsay B, Upadhyaya, Santhosh A, Wetmore, Cynthia, Wright, Karen D, Choi, Jeea, Gasal, Eduard, Russo, Mark W, Fox, Elizabeth
Vydáno v Neuro Oncol (2020)