Natural Products as an Emerging Therapeutic Alternative in the Treatment of Neurological Disorders

av Karim, Nasiara, Abdelhalim, Heba, Gavande, Navnath, Khan, Imran, Khan, Haroon
I publikationen Evid Based Complement Alternat Med (2018)

Characterization of a Drosophila Ortholog of the Cdc7 Kinase: A ROLE FOR Cdc7 IN ENDOREPLICATION INDEPENDENT OF CHIFFON

av Stephenson, Robert, Hosler, Marcus R., Gavande, Navnath S., Ghosh, Arun K., Weake, Vikki M.
I publikationen J Biol Chem (2015)

2′-Methoxy-6-methylflavone: a novel anxiolytic and sedative with subtype selective activating and modulating actions at GABA(A) receptors

av Karim, Nasiara, Curmi, John, Gavande, Navnath, Johnston, Graham AR, Hanrahan, Jane R, Tierney, M Louise, Chebib, Mary
Publicerad 2012

Design, Synthesis, and Pharmacological Evaluation of Fluorescent and Biotinylated Antagonists of ρ(1) GABA(C) Receptors

av Gavande, Navnath, Kim, Hye-Lim, Doddareddy, Munikumar R., Johnston, Graham A. R., Chebib, Mary, Hanrahan, Jane R.
Publicerad 2013

Structure-Guided Optimization of Replication Protein A (RPA)–DNA Interaction Inhibitors

av Gavande, Navnath S., VanderVere-Carozza, Pamela S., Pawelczak, Katherine S., Vernon, Tyler L., Jordan, Matthew R., Turchi, John J.
I publikationen ACS Med Chem Lett (2020)

Design and Structure-Guided Development of Novel Inhibitors of the Xeroderma Pigmentosum Group A (XPA) Protein–DNA Interaction

av Gavande, Navnath S., VanderVere-Carozza, Pamela, Mishra, Akaash K., Vernon, Tyler L., Pawelczak, Katherine S., Turchi, John J.
I publikationen J Med Chem (2017)

Insights into the Mechanism of Inhibition of CXCR4: Identification of Piperidinylethanamine Analogs as Anti-HIV-1 Inhibitors

av Das, Debananda, Maeda, Kenji, Hayashi, Yasuhiro, Gavande, Navnath, Desai, Darshan V., Chang, Simon B., Ghosh, Arun K., Mitsuya, Hiroaki
I publikationen Antimicrob Agents Chemother (2015)

Structure-Based Design of Highly Selective β-Secretase Inhibitors: Synthesis, Biological Evaluation, and Protein-Ligand X-ray Crystal Structure

av Ghosh, Arun K., Rao, Kalapala Venkateswara, Yadav, Navnath D., Anderson, David D., Gavande, Navnath, Huang, Xiangping, Terzyan, Simon, Tang, Jordan
Publicerad 2012

DNA repair targeted therapy: the past or future of cancer treatment?

av Gavande, Navnath S., VanderVere-Carozza, Pamela S., Hinshaw, Hilary D., Jalal, Shadia I., Sears, Catherine R., Pawelczak, Katherine S., Turchi, John J.
I publikationen Pharmacol Ther (2016)

Differentiating Enantioselective Actions of GABOB: A Possible Role for Threonine 244 in the Binding Site of GABA(C) ρ(1) Receptors

av Yamamoto, Izumi, Absalom, Nathan, Carland, Jane E., Doddareddy, Munikumar R., Gavande, Navnath, Johnston, Graham A. R., Hanrahan, Jane R., Chebib, Mary
Publicerad 2012

Novel Cyclic Phosphinic Acids as GABA(C) ρ Receptor Antagonists: Design, Synthesis, and Pharmacology

av Gavande, Navnath, Yamamoto, Izumi, Salam, Noeris K., Ai, Tu-Hoa, Burden, Peter M., Johnston, Graham A. R., Hanrahan, Jane R., Chebib, Mary
Publicerad 2010

Structurally Diverse GABA Antagonists Interact Differently with Open and Closed Conformational States of the ρ(1) Receptor

av Yamamoto, Izumi, Carland, Jane E., Locock, Katherine, Gavande, Navnath, Absalom, Nathan, Hanrahan, Jane R., Allan, Robin D., Johnston, Graham A. R., Chebib, Mary
Publicerad 2012

Discovery and development of novel DNA-PK inhibitors by targeting the unique Ku–DNA interaction

av Gavande, Navnath S, VanderVere-Carozza, Pamela S, Pawelczak, Katherine S, Mendoza-Munoz, Pamela, Vernon, Tyler L, Hanakahi, Leslyn A, Summerlin, Matthew, Dynlacht, Joseph R, Farmer, Annabelle H, Sears, Catherine R, Nasrallah, Nawar Al, Garrett, Joy, Turchi, John J
I publikationen Nucleic Acids Res (2020)

The flavonoid, 2′-methoxy-6-methylflavone, affords neuroprotection following focal cerebral ischaemia

av Clarkson, Andrew N, Boothman-Burrell, Lily, Dósa, Zita, Nagaraja, Raghavendra Y, Jin, Liang, Parker, Kim, van Nieuwenhuijzen, Petra S, Neumann, Silke, Gowing, Emma K, Gavande, Navnath, Ahring, Philip K, Holm, Mai M, Hanrahan, Jane R, Nicolazzo, Joseph A, Jensen, Kimmo, Chebib, Mary
I publikationen J Cereb Blood Flow Metab (2018)